CWShredder didn't do the trick for my polluted PC and my techie fiance working on it; we did the process three times with no luck. A Format C solved the problem nicely, though, and freed up a chunk of space.
Cool Web seems to involve a whole bunch of different sources and different bugs.
The particular problem I had was that one of my kids managed to infect MS Media Player. It LOOKED like media player, but something else had taken its place and disguised itself as Media Player. I had to delete it, clean up the Registry, and re-download Media Player from MS Update. But from the research I did at the time, there are dozens of different things various coolweb leeches can do to your computer, some no doubt worse than others.
Have you downloaded the most recent CWS Shredder? Your version may not have caught the most recent variant of CWS.