I think it gets down to a matter of, what do you intend on using the gun for? Single action triggers are the hands down winner for target shooting or competition, but I still wouldn't want one for open or concealed carry. I know that people swear that it's safe to carry cocked and locked, but I prefer to carry a gun uncocked and I prefer the long, heavy and deliberate trigger pull necessary to fire a DAO pistol if I have to carry it. It's just an extra element of safety that I don't want to give up.
As for DA/SA pistols I really don't like the idea of the trigger pull changing after the first shot. It's hard enough to shoot accurately as it is without your trigger changing.
One of the nice features of the 1911 was the "half cocked" hammer position. It allowed you to keep an extra round in the chamber ready to go.
Being a bad shot I prefer big caliber so in the off chance I hit something it is no longer a threat. Also putting snake shot rounds in the first 3 positions helps in the dark in an emergency.