I wouldn't be so quick to count out Majette. She was able to knock out an entrenched incumbent with strong political family ties in a primary just two years ago. We cheered her on then, and that kind of underdog good will carries a long time.
I have discounted Majette. Georgia is, after November, officially a Republican state from top to bottom. The dim in the U.S. Senate race doesn't stand a chance, even if Isakson does win the Republican nomination. Remember, the underdog win she got was due to Neal Boortz and the Republicans in her district. Those Republicans won't be voting for her in November.