I think you are right. Many of the people playing with this, have no appreciation of the dangers involved.
It's like that one cure that was attempted using a genetically modified virus. It cured the target illness but then killed the patients. But what if that virus had escaped into the wild?
We really need to fully understand the genome before we attempt stuff like this, to the point of being able to model behavior in a computer. Complete with interaction with known viruses, etc.
But if you don't understand it, how will you pass judgement on new procedures?