[ought-six]

"Moral: Don't bring a .22 to a knife fight."

A .22 is not an ideal self-defense round, but it has, at times, done the job. It depends on which round is employed. A .22 WMR can be deadly. A hyper-velocity .22 LR round (such as a CCI Stinger) has been known to get a perpetrator's serious attention, as well. I would not want to use a .22 for self-defense, but if I had to use one, I'd opt for a .22 WMR (preferably), or if I didn't have that, a .22 CCI Stinger. Best self-defense weapon in the world is a 12-gauge pump shotgun with 00-buck.

[AnAmericanMother]

I would haul out my old Webley Army revolver in .455 before I would rely on a .22. It has occasionally done the job, but that's not the way to bet.

Besides, with the ugly old Webley if I run out of ammo I can use the piece as a highly effective blunt instrument.

Only a mother could love this ugly thang.