Indeed, Hollywood monsters seem to be mostly derived from known earthly body plans. IMHO, the aliens in the Star Trek series were more diverse - creatures without structure, micro and macro creatures, collectives, etc.
Loads of new insects are always turning up in the rain forests, but they're still insects. No doubt the oceans still have surprises which await us. However, on land ... it would be quite a trick for a whole new line of evolution to get itself started. It would be foolish to rule it out, but the most favorable time for such developments would seem to be after a mass extinction event. That's how it looks to me.