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Not-So-Intelligent Design
The Scientist ^ | Mar. 4, 2002 | Neil S. Greenspan and Anthony Canamucio

Posted on 03/02/2002 5:10:54 PM PST by Karl_Lembke

The Scientist 16[5]:12, Mar. 4, 2002

OPINION

Not-So-Intelligent Design

By Neil S. Greenspan
Anthony Canamucio

Some members of the Ohio State Board of Education are maneuvering to have "intelligent design" (ID) taught to Ohio students as an alternative to teaching them about biological evolution.1 These board members were pursuing the inclusion of ID in the biology curriculum despite unambiguous opposition from the relevant science advisory committee. One board member apparently regards this development as a chance for Ohio "to be on the cutting edge." Unfortunately, this cutting edge will only serve to whittle away a bit more of the collective intellect of the citizenry of Ohio, and the implications reach much farther than the state's boundaries.

According to the enthusiasts for ID, metabolic systems, such as the clotting cascade, are too complex ("irreducibly complex" in their preferred wording) to have arisen through evolution.2 Problems with this view are readily apparent. First, complexity is problematic to define, and irreducible complexity more so.

At present, it is doubtful whether it is possible to measure, prospectively and precisely, the complexity of biological systems so as to distinguish systems that are irreducibly complex from those that are reducibly complex. The concept of irreducible complexity is simply asserted; it is not based on either evidence or compelling logic. Consequently, proponents of ID must decide, essentially arbitrarily, what is too complex to have evolved. They can claim that all of life is too complex to have evolved. Or, are we to believe that bacteria evolved but that humans (or mammals, or whatever groups of organisms) were designed? Would it make any more sense the other way around?

A truly fundamental problem with the notion of ID, as a scientific idea, is that, ultimately, it has effectively no explanatory or predictive power. Suggesting that an unknown Intelligent Designer of unspecified attributes designed the eye, the clotting cascade, or the immune system offers no scientific insights into these biologic marvels and suggests no incisive experiments. There is also the nagging issue of how the Intelligent Designer implements designs without being noticed. How do ID proponents explain the existence of defective genes, no longer capable of expression, in one species that are strikingly similar to still functional genes in a related species? What insights does ID provide in accounting for the origin and spread of bacterial resistance to antibiotics? These phenomena are consistent with the principles of evolution, which find application from the molecular level to the level of ecosystems.

Were the genes associated with conditions such as sickle cell disease or cystic fibrosis designed by The Intelligent Designer, or by her sister, The Not-So-Intelligent Designer? If the response is that we do not understand the motives or goals of the Designer, then of what use is it to posit this inscrutable being in explaining such realities as the relatively high frequencies of these genes in the human population.

On the other hand, evolutionary principles provide a compelling rationale for the high prevalence of the b-globin allele associated with sickle cell disease: in a single copy it provides protection from the deadliest effects of one type of malaria parasite. Consistent with this hypothesis, sickle cell disease is prevalent almost exclusively in populations that live in, or are descended from those who lived in, malaria-endemic regions of the globe. Whereas some ID advocates suggest that mutations are uniformly harmful, there are thoroughly documented human mutations, such as the mutation associated with sickle cell disease, that are alternately harmful or beneficial depending on the exact genotype and the environmental circumstances.

Enthusiasts for ID ignore the growing laboratory evidence for the selection of biological function from random collections of proteins and nucleic acids.3,4 Molecular biologists and biotechnologists have shown that selection acting on randomly generated libraries of billions or trillions of biological polymers, such as peptides or RNA molecules, can produce molecules with useful biological functions, such as specificities for small ligands or catalytic activities. Computer scientists, complexity theorists, and even physical chemists have also documented striking examples of order that develops spontaneously.5,6 It is simply no longer tenable to equate order, complex structure, or sophisticated function uniquely with conscious design.

The Design advocates also ignore the accumulating examples of the reducibility of biological systems. As Russell Doolittle has noted in commenting on the writings of one ID advocate, mice genetically altered so that they lack either thrombin or fibrinogen have the expected abnormal hemostatic phenotypes.7 However, when the separate knockout mice are bred, the double knockouts apparently have normal hemostasis (reducible complexity after all), at least in the laboratory.8 These results cast doubt on the claim by proponents of ID that they know which systems exhibit irreducible complexity and which do not.

Evolution is best regarded as a fact. What is more, it is a fact that is inescapable. The resistance of bacteria to overused antibiotics, viruses to inhibitors of viral replication, and insects to pesticides, are all examples of the evolutionary process in operation. If you do research with cells or microorganisms, genetic variation and selection are continuously in evidence, even when you would prefer them not to be. Thus, that evolution occurs, and has occurred, is not in doubt. It has been directly observed in operation not only in the laboratory but also in the field.9 Where there is still room for argument and discussion is in the precise contributions of different mechanisms to evolutionary change. In this vibrant debate, intelligent design offers no meaningful contribution.

The effort to insert nonscientific ideas into Ohio's science curriculum is being carried out under the banner of promoting critical thinking.10 Perhaps other scientists will be as surprised as I was to learn that the education bill, "No Child Left Behind," signed into law by President George W. Bush on Jan. 8, originally contained an amendment from US Sen. Rick Santorum (R-Pa.). This amendment, ultimately removed from the bill, comprises the following two statements: "It is the sense of the Senate that: (1) good science education should prepare students to distinguish the data or testable theories of science from philosophical or religious claims that are made in the name of science; and (2) where biological evolution is taught, the curriculum should help students to understand why the subject generates so much continuing controversy, and should prepare the students to be informed participants in public discussions regarding the subject."

It would appear that a new and clever strategy has been found to get religious ideas into biology class. Those in other states concerned that the science curriculum remains focused on science should be vigilant against similar campaigns in their own states. Otherwise, they could find that the officials crafting the science curriculum for their schools are engaged in a process that comes closer to deserving the label "subversive design" rather than "intelligent design."

Neil S. Greenspan, MD-PhD, is professor of pathology at the Institute of Pathology, Case Western Reserve University, Euclid Avenue, Cleveland, OH 44106-4943.

References
1. J. Mangels, S. Stephens, "Evolution targeted in curriculum study," The Plain Dealer, Jan. 15, 2002, pp. A1, A9.
2. M.J. Behe, Darwin's black box: The biochemical challenge to evolution, New York: Free Press, 1997.
3. J.R. Lorsch, J.W. Szostak, "Chance and necessity in the selection of nucleic acid catalysts," Accounts of Chemical Research, 29[2]:103-10, 1996.
4. J.K. Scott, G.P. Smith, "Searching for peptide ligands with an epitope library," Science, 249:386-90, 1990.
5. S.A. Kauffman, The origins of order: Self-organization and selection in evolution," New York: Oxford University Press, 1993.
6. D. Kestenbaum, "Gentle force of entropy bridges disciplines," Science, 279,1849, 1998.
7. R. F. Doolittle, R.F. "A delicate balance," Boston Review, February/March 1997, or online at bostonreview.mit.edu/br22.1/doolittle.html.
8. T.H. Bugge, "Loss of fibrinogen rescues mice from the pleiotropic effects of plasminogen deficiency," Cell, 87:709-19, 1996.
9. J. Weiner, The beak of the finch: A story of evolution in our time, New York: Alfred A. Knopf, 1994.
10. R. Lattimer, J. Calvert, "Intelligent design is a matter of academic freedom," The Plain Dealer, Jan. 18, 2002, p. B9.

The Scientist 16[5]:12, Mar. 4, 2002


TOPICS: Culture/Society; Editorial
KEYWORDS: crevolist; educationnews; ohio; sasu
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To: Exnihilo
The gaul of the naturalists to sit there and honestly claim that they are some how "more objective" than the opposition is the height of absurdity.

A height equalled frequently by literal Creationists when they beat their heads against the wall with the same bad science over and over again.

I find it a reasonably accurate prejudice to assume that Creationists make bad scientists and Evolutionists make bad theologians.

I will agree that Evolutionists are not so aware as they should be when they are tramping in theological woods.




41 posted on 03/02/2002 7:15:48 PM PST by Sabertooth
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To: Sabertooth
Again, I'd ask, as I've done a thousand times before on these threads that never end, for a complete and thorough definition of "Creationist" that we can all agree on. Clearly, scientific data would conflict with a literal 6-day interpretation of Genesis. That being said, what is a "Creationist" and why do you think it is that the naturalists who adhere to Darwinian orthodoxy shout "Creationist!" at their opposition as though they were shining a bright light on a dark corner of the world and exposing something? It's quite telling that the mere accusation is something that, presumably, is to be feared, avoided, and skirted at all costs in order to remain in good intellectual standing with the naturalists.
43 posted on 03/02/2002 7:20:05 PM PST by Exnihilo
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To: coteblanche
We have alway done it that way and will alway do it that way because we have faith. The earth is the center of the universe, the earth is flat, We can't fly, we can't do surgery, we must not deal with DNA. We can only pray in a dead language. If we get sick its not a problem, its gods idea so chill. If god wanted us to be cold, wet and hungrey he would have made us that way.
44 posted on 03/02/2002 7:26:15 PM PST by earplug
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To: Exnihilo
Again, I'd ask, as I've done a thousand times before on these threads that never end, for a complete and thorough definition of "Creationist" that we can all agree on. Clearly, scientific data would conflict with a literal 6-day interpretation of Genesis. That being said, what is a "Creationist" and why do you think it is that the naturalists who adhere to Darwinian orthodoxy shout "Creationist!" at their opposition as though they were shining a bright light on a dark corner of the world and exposing something?

Well, I believe that God is the Author of the Universe and spoke it into being about 15 or so billion years ago... and things have been running more or less mechanistically ever since. So you could define Creationist broadly enough to include me, I suppose.

But I think a better definition of Creationist would be anyone who believes in Special Creation of species, regardless of time frame. That's neither provable nor disprovable, scientifically.

At that point, we'd also have to accept that the Universe was created yesterday, or tomorrow, as valid scientific theories. That's all deus ex machina, and not too compelling.


46 posted on 03/02/2002 7:32:37 PM PST by Sabertooth
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To: earplug
Your reasoning is truly dizzying.
47 posted on 03/02/2002 7:33:44 PM PST by Exnihilo
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To: Karl_Lembke
Were the genes associated with conditions such as sickle cell disease or cystic fibrosis designed by The Intelligent Designer, or by her sister, The Not-So-Intelligent Designer?

This flippant comment shows a total lack of respect, even animosity, for a belief in God and for religion in general. How fair and scientific a review of the possiblities of intellegent design could be expected from this articles authors, Greenspan and Canamucio? After reading that sentence, I expected no fairness or scientific accuracy at all, and thats just what they delivered in the article.

None of the arguments they put forth give even the slightest proof that intellgent design could not be involved in all of the cited biological processes. Replace "evolution" in their article with "adaptation by intelligent design," and the same processes can be explained.

To answer the question of defects in mankind, when did we expect perfection in man on earth? I've never seen it, and it isn't in the bible except for on man, and he wasn't perfect physically, just spiritually.

48 posted on 03/02/2002 7:37:46 PM PST by Enlightiator
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To: earplug; coteblanche
What's the problem with saying at some point, "Science can't answer, or hasn't answered that?"

Here's what coteblanche was replying to when she made her comment about faith. She wasn't arguing against a properly agnostic science, she was simply agreeing with the point that not all truths can be reached through science.

Just as I'm sure she'd agree that not all science can be discovered by faith.

Do you disagree?




49 posted on 03/02/2002 7:39:48 PM PST by Sabertooth
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To: Exnihilo
The main failing (the big one) is that Dembski never defines his term "specified complexity" in a biologically meaningful way. He talks about as though evolution is aiming at a target. It is not. Evolution is a process, not a goal.

In other cases, he suggests an evolutionary path and then rejects that path. Other critics (you should read them) point out that there are other mechanisms which Dembski ignores.

There are no examples of something designed vs something not designed for comparison. If everything is designed, the theory is vacuous.

50 posted on 03/02/2002 7:45:17 PM PST by Doctor Stochastic
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To: Doctor Stochastic
There are no examples of something designed vs something not designed for comparison. If everything is designed, the theory is vacuous.

If nothing is designed, or if everything is random, would that theory also be vacuous?




52 posted on 03/02/2002 7:48:12 PM PST by Sabertooth
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To: Sabertooth
No. The claim that everything is random is not vacuous (not necessarily true, however.) Design is arbitrary; anything can be said to happen "because the designer did it." One can distinguish random from chaotic for example.
53 posted on 03/02/2002 7:52:15 PM PST by Doctor Stochastic
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To: Sabertooth
"I find it a reasonably accurate prejudice to assume that Creationists make bad scientists and Evolutionists make bad theologians."

I realize that you mean this more or less as jest. But truth is, many of the great Western scientists of the last five centuries were religious Christians (therefore creationists), some extremely devout.
54 posted on 03/02/2002 7:52:44 PM PST by Texas_Jarhead
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To: gcruse
"Religion, the weapon of choice in the attack on human advancement."

Another intellectual nugget from a secular extremist. Why don't you try learning a little bit about the real contributions made by religion to mankind. The data is available, all you have to do if look for it.

FReegards,
Right wing caveman
55 posted on 03/02/2002 7:53:24 PM PST by Texas_Jarhead
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To: Doctor Stochastic
Design is arbitrary; anything can be said to happen "because the designer did it."

How is "random did it" any different, or any less arbitrary?




56 posted on 03/02/2002 7:59:16 PM PST by Sabertooth
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To: adakotab
Apparently the author hasn't read much, if anything, of William Dembski's articles on Intelligent Design. Dembski explains in detail how irreducible complexity is determined.

Dembski is a snake oil peddler. He capitalizes on the fact that most people do not understand information theory and the fact that pedestrian definitions of the words he uses are actually inadequate or incorrect when applied to the field of mathematics. He weaves a good story, but it is basically incorrect mathematics dressed up to look reasonable to people who don't understand the field. I work in the field of mathematics that he purports to be using, so his misuse of the mathematics is pretty transparent to me. (That and he "proves" mathematical concepts by anecdote. As though that was ever a valid approach.)

I don't care what Dembski's position is; his mathematics and "proofs" are wrong regardless.

57 posted on 03/02/2002 8:00:14 PM PST by tortoise
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To: Sabertooth
Of course, you're right in some sense: one cannot disprove intelligent design because one can always speculate that something has been designed.
Take a rock for example: it could have formed naturally over millions of years or in a volcanic eruption and have been exposed to erosion or an intelligent designer who is able to manipulate matter on the atomic level created it. One can't even rule out the fact that our universe has been created last Tuesday by an omnipotent deity.
Such hypothesis can be neither confirmed nor completely ruled out and therefore they're not scientific.

But even if we discover Laws of Biology, as we have Laws of Physics and Chemistry, we will forever beg the question (scientifically, anyway) of how and why those laws came to be...

And the same was true for lightning up until some two hundred years ago. People begged the question of how and why lightnings happend. They invented deities like Thor or Zeus and numerous others who were thought to cause this phenomenon. Were they right? I don't know but today we have a naturalistic explanation for this phenomenon so we don't need these deities anymore.

Today it isn't lightning we're preoccupied with but more complex issues like the ones you named above. Of course we can ascribe them to some god but this "explanation" may be too discarded if a naturalistic explanation is available. Therefore I tend to say that I don't know rather than to assert that it must be the work of a deity. So there's absolutely no problem with saying that "science hasn't found out yet" but we can't state with absolute certainty that science will never answer a certain issue.

The problem I see with supernaturalistic explanations is that one cannot determine whether there is no naturalistic explanation left so there is only the option to evoke the supernatural or whether there exists a naturalistic explanation but we haven't looked hard enough.

Just my 0.02$

58 posted on 03/02/2002 8:04:40 PM PST by BMCDA
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To: Texas_Jarhead
But truth is, many of the great Western scientists of the last five centuries were religious Christians (therefore creationists), some extremely devout.

Very true. Isaac Newton considered himself to be a deeply religious theologian first and foremost; the work he did in physics and mathematics was a side hobby and many times was pursued to prove some religious point. As it happens, Newton's theological writings make him look raving mad even to the most ardent supporters of Christianity, hence why he is generally only remembered for his work in mathematics and physics.

An oft observed trait of brilliant scientists is that they do most of their best work when they are very young and rapidly slip into mediocrity and nuttiness with age. Einstein is an example of someone who was brilliant in his twenties but essentially became a crank with some dubious beliefs and ideas when he was in his middle age. It is mistaken to assume that brilliant people are always right or even rational.

59 posted on 03/02/2002 8:10:55 PM PST by tortoise
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To: earplug
I like your style. LOL
60 posted on 03/02/2002 8:12:01 PM PST by gcruse
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