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Not-So-Intelligent Design
The Scientist ^ | Mar. 4, 2002 | Neil S. Greenspan and Anthony Canamucio

Posted on 03/02/2002 5:10:54 PM PST by Karl_Lembke

The Scientist 16[5]:12, Mar. 4, 2002

OPINION

Not-So-Intelligent Design

By Neil S. Greenspan
Anthony Canamucio

Some members of the Ohio State Board of Education are maneuvering to have "intelligent design" (ID) taught to Ohio students as an alternative to teaching them about biological evolution.1 These board members were pursuing the inclusion of ID in the biology curriculum despite unambiguous opposition from the relevant science advisory committee. One board member apparently regards this development as a chance for Ohio "to be on the cutting edge." Unfortunately, this cutting edge will only serve to whittle away a bit more of the collective intellect of the citizenry of Ohio, and the implications reach much farther than the state's boundaries.

According to the enthusiasts for ID, metabolic systems, such as the clotting cascade, are too complex ("irreducibly complex" in their preferred wording) to have arisen through evolution.2 Problems with this view are readily apparent. First, complexity is problematic to define, and irreducible complexity more so.

At present, it is doubtful whether it is possible to measure, prospectively and precisely, the complexity of biological systems so as to distinguish systems that are irreducibly complex from those that are reducibly complex. The concept of irreducible complexity is simply asserted; it is not based on either evidence or compelling logic. Consequently, proponents of ID must decide, essentially arbitrarily, what is too complex to have evolved. They can claim that all of life is too complex to have evolved. Or, are we to believe that bacteria evolved but that humans (or mammals, or whatever groups of organisms) were designed? Would it make any more sense the other way around?

A truly fundamental problem with the notion of ID, as a scientific idea, is that, ultimately, it has effectively no explanatory or predictive power. Suggesting that an unknown Intelligent Designer of unspecified attributes designed the eye, the clotting cascade, or the immune system offers no scientific insights into these biologic marvels and suggests no incisive experiments. There is also the nagging issue of how the Intelligent Designer implements designs without being noticed. How do ID proponents explain the existence of defective genes, no longer capable of expression, in one species that are strikingly similar to still functional genes in a related species? What insights does ID provide in accounting for the origin and spread of bacterial resistance to antibiotics? These phenomena are consistent with the principles of evolution, which find application from the molecular level to the level of ecosystems.

Were the genes associated with conditions such as sickle cell disease or cystic fibrosis designed by The Intelligent Designer, or by her sister, The Not-So-Intelligent Designer? If the response is that we do not understand the motives or goals of the Designer, then of what use is it to posit this inscrutable being in explaining such realities as the relatively high frequencies of these genes in the human population.

On the other hand, evolutionary principles provide a compelling rationale for the high prevalence of the b-globin allele associated with sickle cell disease: in a single copy it provides protection from the deadliest effects of one type of malaria parasite. Consistent with this hypothesis, sickle cell disease is prevalent almost exclusively in populations that live in, or are descended from those who lived in, malaria-endemic regions of the globe. Whereas some ID advocates suggest that mutations are uniformly harmful, there are thoroughly documented human mutations, such as the mutation associated with sickle cell disease, that are alternately harmful or beneficial depending on the exact genotype and the environmental circumstances.

Enthusiasts for ID ignore the growing laboratory evidence for the selection of biological function from random collections of proteins and nucleic acids.3,4 Molecular biologists and biotechnologists have shown that selection acting on randomly generated libraries of billions or trillions of biological polymers, such as peptides or RNA molecules, can produce molecules with useful biological functions, such as specificities for small ligands or catalytic activities. Computer scientists, complexity theorists, and even physical chemists have also documented striking examples of order that develops spontaneously.5,6 It is simply no longer tenable to equate order, complex structure, or sophisticated function uniquely with conscious design.

The Design advocates also ignore the accumulating examples of the reducibility of biological systems. As Russell Doolittle has noted in commenting on the writings of one ID advocate, mice genetically altered so that they lack either thrombin or fibrinogen have the expected abnormal hemostatic phenotypes.7 However, when the separate knockout mice are bred, the double knockouts apparently have normal hemostasis (reducible complexity after all), at least in the laboratory.8 These results cast doubt on the claim by proponents of ID that they know which systems exhibit irreducible complexity and which do not.

Evolution is best regarded as a fact. What is more, it is a fact that is inescapable. The resistance of bacteria to overused antibiotics, viruses to inhibitors of viral replication, and insects to pesticides, are all examples of the evolutionary process in operation. If you do research with cells or microorganisms, genetic variation and selection are continuously in evidence, even when you would prefer them not to be. Thus, that evolution occurs, and has occurred, is not in doubt. It has been directly observed in operation not only in the laboratory but also in the field.9 Where there is still room for argument and discussion is in the precise contributions of different mechanisms to evolutionary change. In this vibrant debate, intelligent design offers no meaningful contribution.

The effort to insert nonscientific ideas into Ohio's science curriculum is being carried out under the banner of promoting critical thinking.10 Perhaps other scientists will be as surprised as I was to learn that the education bill, "No Child Left Behind," signed into law by President George W. Bush on Jan. 8, originally contained an amendment from US Sen. Rick Santorum (R-Pa.). This amendment, ultimately removed from the bill, comprises the following two statements: "It is the sense of the Senate that: (1) good science education should prepare students to distinguish the data or testable theories of science from philosophical or religious claims that are made in the name of science; and (2) where biological evolution is taught, the curriculum should help students to understand why the subject generates so much continuing controversy, and should prepare the students to be informed participants in public discussions regarding the subject."

It would appear that a new and clever strategy has been found to get religious ideas into biology class. Those in other states concerned that the science curriculum remains focused on science should be vigilant against similar campaigns in their own states. Otherwise, they could find that the officials crafting the science curriculum for their schools are engaged in a process that comes closer to deserving the label "subversive design" rather than "intelligent design."

Neil S. Greenspan, MD-PhD, is professor of pathology at the Institute of Pathology, Case Western Reserve University, Euclid Avenue, Cleveland, OH 44106-4943.

References
1. J. Mangels, S. Stephens, "Evolution targeted in curriculum study," The Plain Dealer, Jan. 15, 2002, pp. A1, A9.
2. M.J. Behe, Darwin's black box: The biochemical challenge to evolution, New York: Free Press, 1997.
3. J.R. Lorsch, J.W. Szostak, "Chance and necessity in the selection of nucleic acid catalysts," Accounts of Chemical Research, 29[2]:103-10, 1996.
4. J.K. Scott, G.P. Smith, "Searching for peptide ligands with an epitope library," Science, 249:386-90, 1990.
5. S.A. Kauffman, The origins of order: Self-organization and selection in evolution," New York: Oxford University Press, 1993.
6. D. Kestenbaum, "Gentle force of entropy bridges disciplines," Science, 279,1849, 1998.
7. R. F. Doolittle, R.F. "A delicate balance," Boston Review, February/March 1997, or online at bostonreview.mit.edu/br22.1/doolittle.html.
8. T.H. Bugge, "Loss of fibrinogen rescues mice from the pleiotropic effects of plasminogen deficiency," Cell, 87:709-19, 1996.
9. J. Weiner, The beak of the finch: A story of evolution in our time, New York: Alfred A. Knopf, 1994.
10. R. Lattimer, J. Calvert, "Intelligent design is a matter of academic freedom," The Plain Dealer, Jan. 18, 2002, p. B9.

The Scientist 16[5]:12, Mar. 4, 2002


TOPICS: Culture/Society; Editorial
KEYWORDS: crevolist; educationnews; ohio; sasu
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Consider another fire lit.....
1 posted on 03/02/2002 5:10:54 PM PST by Karl_Lembke (karl@bbs.annex.com)
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To: crevo_list
Onto list.
2 posted on 03/02/2002 5:12:16 PM PST by Karl_Lembke
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To: Karl_Lembke
Wake up people the "missing link" was never found. The whole dam chain is missing.

If they're going to teach the religion of Evolution then by all means teach Creation.

3 posted on 03/02/2002 5:15:33 PM PST by arepublicifyoucankeepit
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To: arepublicifyoucankeepit
"subversive design"

Religion, the weapon of choice
in the attack on human advancement.

4 posted on 03/02/2002 5:29:19 PM PST by gcruse
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To: Karl_Lembke
The concept of irreducible complexity is simply asserted; it is not based on either evidence or compelling logic. Consequently, proponents of ID must decide, essentially arbitrarily, what is too complex to have evolved.

Apparently the author hasn't read much, if anything, of William Dembski's articles on Intelligent Design. Dembski explains in detail how irreducible complexity is determined.

Par for the course from some evolutionists to cry deceit while themselves deceiving.

5 posted on 03/02/2002 5:32:16 PM PST by adakotab
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To: adakotab
Another problem caused by "winner take all" public schools. If we had school choice, I could send my kids to a school that taught evolution, and religious people could send their kids to a school that taught creationism.
6 posted on 03/02/2002 5:45:52 PM PST by marktwain
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To: Karl_Lembke
Smug pseudo-scientists. Intelligent Design and General Evolution are both theories put forward to explain the evidence. Intelligent Design makes some sense. General Evolution doesn't. Freud and Marx have both been widely discredited among people with sense, and Darwin is next on the list.
7 posted on 03/02/2002 5:46:00 PM PST by Cicero
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To: gcruse
I think a loving god would have told us to boil water, wash often with soap and avoid lead, mercury, arsenic and fleas. But we pay our 10% and hope for eternal life. I feel so warm and fuzzy.
8 posted on 03/02/2002 5:50:32 PM PST by earplug
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To: Karl_Lembke
"How do ID proponents explain the existence of defective genes, no longer capable of expression, in one species that are strikingly similar to still functional genes in a related species? "

It seems the author of this article has seiously misunderstood ID. First of all, ID is NOT the same thing as "Perfection of Design, nor does it categorically deny evolution.

For crying out loud, even the Six-Day creationists believe in evolution of a degradationist type (the gradual loss or invalidation of information).

9 posted on 03/02/2002 5:51:07 PM PST by cookcounty
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To: Karl_Lembke
It's easier to believe in the Easter Bunny or Santa Claus than the Theory of Evolution. So much evidence is piling up to discredit evolution. The emperor has no clothes any more, never did.
10 posted on 03/02/2002 5:55:38 PM PST by AmericaUnited
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To: earplug
I think a loving god would have told us to boil water, wash often with soap and avoid lead, mercury, arsenic and fleas.

He did, by giving you a brain. You do know about those things. Thank God.

11 posted on 03/02/2002 5:57:46 PM PST by AmericaUnited
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To: cookcounty
Wrong about the six day creationists....read "Genesis and The Big Bang" and "The Science of God" by Doctor Gerald L. Schroeder.
12 posted on 03/02/2002 5:58:22 PM PST by TailspinJim
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To: Karl_Lembke
"First, complexity is problematic to define, and irreducible complexity more so."

Oh, give me a break. The reason that we would be surprised to find a mushroom having a litter of puppies is that it is far too COMPLX of a transformation.

"Can't define 'complexity.'" Don't be silly.

13 posted on 03/02/2002 6:00:57 PM PST by cookcounty
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Comment #14 Removed by Moderator

To: TailspinJim
I haven't read Schroeder, but I have to say, I'm sure you're mistaken. The idea of harmful mutations taking hold in a population are widely suported by 6-dayers. (are you saying they believe all mutations are neutral, or that they don't believe there are mutations?)
15 posted on 03/02/2002 6:11:09 PM PST by cookcounty
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To: adakotab
Dembski explains in detail how irreducible complexity is determined.

Yeah, he makes up odds for things that have already occurred. Most people can understand the folly of that.

For instance, calculate the odds that at this moment I just picked up a pencil. Using Dumbowski's method, he'd compute a series of improbabilities and say that the chance of me picking up a pencil just then is 1 in 10^76.

Of course, I did pick up the pencil, so there is no probability calculation that matters. It is a certainty. It already happened. Applying probability to prove it couldn't or didn't happen is hilariously inane.

But that's all ID has. Too bad for them.

16 posted on 03/02/2002 6:15:15 PM PST by jlogajan
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To: LincolnDefender
"Really. Could you list the 5 most cited, peer reviewed articles, of 2001 that discredit evolution?"

Please list 5 journals that will accept non-evolutionary viewpoints for peer review. OK, name one, then. You can't complain about lack of peer-reviewed articles, if such articles are, a priori ruled out. It's an illogical question you suggest.

17 posted on 03/02/2002 6:19:29 PM PST by cookcounty
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To: AmericaUnited
I think a loving god would have told us to boil water, wash often with soap and avoid lead, mercury, arsenic and fleas.

He did, by giving you a brain. You do know about those things. Thank God.

Oh? I recall that in the Roman Empire, a very popular type of ceramic used in pots & mugs & wine bottles was high in lead. Rome, of course, was by far the most advanced society in Europe/Africa at the time. Far more advanced than God's favorite tribe was at the time.

Mercury was used for a number of things until recently that would make us blanch. And wasn't arsenic used in patent medicines as a pick-me-up? Or was that strychnine? (Actually, consulting my 1912 New Standard Formulary, all three, sometimes together. Yikes!)

You do realize of course how we did eventually learn why we should avoid lead, arsenic, mercury, & fleas? Godless, philosophically materialistic science! (Oh the horror :-)

18 posted on 03/02/2002 6:28:23 PM PST by jennyp
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To: cookcounty;LincolnDefender;AmericaUnited
OK, how about if we rephrase the question...

Could you list the 5 best arguments as of 2001 that discredit evolution?

19 posted on 03/02/2002 6:33:02 PM PST by jennyp
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To: jlogajan
"Yeah, he makes up odds for things that have already occurred. Most people can understand the folly of that."

But lots of us can't understand it.

The example of your intelligent mind choosing to pick up a pencil is not a particularly cogent argument for the power of random non-intelligent processes.

How about this: You come to my house and find 10,000 pennies on the driveway, all facing heads up. Then I tell you they got that way by my flipping them out the window.

You express your skepticism about my flippping the coins.

Then I explain: 'You can't argue with it. It's already happened!

20 posted on 03/02/2002 6:36:29 PM PST by cookcounty
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