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To: AndrewC
That is not what the lactose intolerance article shows. The population studied was of lactose intolerant individuals. The statement about lactose tolerance was therefore speculation.

The group studied DNA from adults who were lactose intolerant and compared them to sequences from adults who were lactose tolerant. They found that the specific mutations accounting for lactose intolerance were all in the same region of DNA (outside of the coding region btw), identical for peoples from widely ranging geographical areas. What's more, lactose intolerance (non-persistence) is more prevalent than lactose persistence. It's an obvious conclusion that that lactose intolerance is the normal, baseline condition.

You were bringing up infant lactose intolerance in the context of this study, even after I pointed out that this was an unrelated condition. In this congenital disease, the lactase enzyme is completely missing or non-functional. It has nothing to do with the recent study of adult lactose persistence.

123 posted on 02/09/2002 1:13:22 PM PST by Nebullis
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To: Nebullis
What's more, lactose intolerance (non-persistence) is more prevalent than lactose persistence.

This and the preceeding are a wealth of information not provided in the thread where this was discussed. It was stated in the thread that the search for the cause of the condition was located out of the area for the lactase gene, since no mutation had been found in that area. It was not stated that any comparison was made to any other group. The relative frequency of the lactose intolerant condition was also not mentioned. I'm not sure how these numbers from the NIH fit in.

Lactose intolerance

Between 30 and 50 million Americans are lactose intolerant. Certain ethnic and racial populations are more widely affected than others. As many as 75 percent of all African-Americans and Native Americans and 90 percent of Asian-Americans are lactose intolerant. The condition is least common among persons of northern European descent.

141 posted on 02/09/2002 10:10:24 PM PST by AndrewC
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