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But all of this talk about genetic manipulation is really quite silly. If we are going to paint the next generation of "humans" with new brushes, e.g. genetic manipulation, then why not paint on new canvases as well, e.g. silicon? Why limit ourselves to biological beings? Why not become AI robots with infinite lifespans ... or at least lifespans only limited by being obsoleted by the next generation of AI robots?

Good point. If immortality and freedom from pain and disease are the goals then lose the bio-bodies. Nothing but trouble with flesh. But there is one more thing the proto-evolutionists need to fix and fix fast. Emotions. Breed out anger and jealousy and do it quick or the Cro-Magnon non-geno-breeders may rise up and kill the genoid-freaks. Especially in your scenario. We all know how quickly our new Dell becomes a dinosaur. Imagine being an AI lifeform with a lifespan of 10,000 years and next years improvements make you look pathetic. No room for ego there.

Ahhh, but the slow witted barbarian bio-breeders couldn't topple the empires of Science, I hear the techno-wizards say! Unless 19 or 20 of them got control of 3 or 4 airplanes and managed to destroy the economic infra-structure one day.

So which gene sequence is it that controls emotions again?

I imagine that the "bioists" or "silocophobes" will decide they would rather be freakish and alive rather than perfectly human and dead.

Over time they will engineer themselves into something probably like small gazelles that can burrow and swim and run real fast, and maybe even glide like flying squirrels. They'll need to engineer all of those adaptions to keep out of the crosshairs of the AI robots.

Of course the AI robots will counter by de-biologizing earth, i.e paving it completely over with chlorine-gas-infused asphalt.

It will be very hard for what is left of the freakish bioists to live off the land while it is being transformed by the "transhumans"!