'Suicide tree' toxin is 'perfect' murder weapon

New Scientist.com ^ | November 26, 2004 | by James Randerson

[aculeus]

A plant dubbed the suicide tree kills many more people in Indian communities than was previously thought. The warning comes from forensic toxicologists in India and France who have conducted a review of deaths caused by plant-derived poisons.

Cerbera odollam, which grows across India and south-east Asia, is used by more people to commit suicide than any other plant, the toxicologists say. But they also warn that doctors, pathologists and coroners are failing to detect how often it is used to murder people.

A team led by Yvan Gaillard of the Laboratory of Analytical Toxicology in La Voulte-sur-Rhône, France, documented more than 500 cases of fatal Cerbera poisoning between 1989 and 1999 in the south-west Indian state of Kerala alone. Half of Kerala’s plant poisoning deaths, and one in 10 of all fatal poisonings, are put down to Cerbera.

But the true number of deaths due to Cerbera poisoning in Kerala could be twice that, the team estimates, as poisonings are difficult to identify by conventional means.

Unnoticed homicides

Using high-performance liquid chromatography coupled with mass spectrometry to examine autopsy tissues for traces of the plant, the team uncovered a number of homicides that would otherwise have gone unnoticed. This also suggests that some cases put down to suicide may actually have been murders, they say.

Although the kernels of the tree have a bitter taste, this can be disguised if they are crushed and mixed with spicy food. They contain a potent heart toxin called cerberin, similar in structure to digoxin, found in the foxglove.

Digoxin kills by blocking calcium ion channels in heart muscles, which disrupts the heartbeat. But while foxglove poisoning is well known to western toxicologists, Gaillard says pathologists would not be able to identify Cerbera poisoning unless there is evidence the victim had eaten the plant. “It is the perfect murder,” he says.

Three-quarters of Cerbera victims are women. The team says that this may mean the plant is being used to kill young wives who do not meet the exacting standards of some Indian families. It is also likely that many cases of homicide using the plant go unnoticed in countries where it does not grow naturally.

Journal reference: Journal of Ethnopharmacology (vol 95, p 123)

© Copyright Reed Business Information Ltd.

[Velveeta]

ping to 19

Whaddayathink?

[hellinahandcart]

Gardener, surfing. This article came up first on a search of "foxglove" and "toxin".

Been doing the same. I finally have *dirt* for the first time in my life, and have been either planting or looking up plants on Google for the past six weeks.

Would you believe I planted foxgloves? LOL!