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Movie stars get hung up on KGB's anti-hangover drug
Guardian Unlimited ^ | September 23, 2003 | Nick Paton Walsh

Posted on 09/23/2003 4:39:29 AM PDT by Pan_Yans Wife

A drug created by the former KGB to keep its agents sober so that they could drink opponents under the table before stealing their secrets is being sold on the internet to Hollywood stars as a defence against hangovers.

The drug, known as RU-21, is made in Russia and sold as a natural remedy on the internet. Hollywood actors are said to be fond of the fix, called after the American legal drinking age, which enables them to make the most of LA's party circuit without red eyes or pounding headaches detracting from their delivering the goods on the film set next morning.

Its makers claim that it stops the body making an enzyme which turns alcohol into acetaldehyde, a toxic chemical which can damage tissues.

The pill lets you get drunk, but indefinitely delays the hangover and damage to the body's organs.

A little less convenient, the makers say that you have to take two pills before or during every two drinks - a suspicious activity in trendy watering holes.

The KGB invented the drug just after the second world war.

The secrets of the pill were declassified in 1999, and it was developed into a market commodity by scientists at the Russian Academy of Sciences as part of an extended study of alcohol's effects on the body. Its makers and Californian marketeers say it is selling to the tune of $10,000 (£6,000) a week.

"Russians can out-drink anybody in the world anyway," said Emil Chiaberi, head of Spirit Sciences, which sells the pill in the US.

"I don't know why they needed a pill."


TOPICS: Culture/Society; News/Current Events; Russia
KEYWORDS: alcohol; alcoholism; antihangover; avoidconsequences; chemicalresearch; coldwar; drinking; drug; drugs; drunks; espionage; hedonists; hollywood; internet; kgb; libertines; permissivesociety; remedy; ru21; russia; spies
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To: mattdono
Those days are gone and, actually, not missed at all.

I grew up in a household where alcohol was consummed daily, but I never thought about it. I thought it was normal. Then when I got older, and didn't become that attracted to regular drinking, I realized that others might find this behavior strange, too.

To each, his own. But, as you say, I don't miss it. Again, I only drink on occasion, not even monthly for that matter.

Being married to a man who has never consummed alcohol, helps curb my desire to drink, too. It is no fun, drinking alone.

21 posted on 09/23/2003 5:58:21 AM PDT by Pan_Yans Wife ("Life isn't fair. It's fairer than death, is all.")
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To: Mackey
I've certainly grown older, but I'm still waiting for that darn wiser part to kick in.
22 posted on 09/23/2003 6:02:31 AM PDT by metesky (("Brethren, leave us go amongst them." Rev. Capt. Samuel Johnston Clayton - Ward Bond- The Searchers)
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To: PeterPrinciple
I think my mother prayed hangovers on me when I was a kid....it worked.

Should the need arise, I will employ the same tactic with my children! You have a wise mother!

23 posted on 09/23/2003 6:03:55 AM PDT by Pan_Yans Wife ("Life isn't fair. It's fairer than death, is all.")
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To: Pan_Yans Wife
The hollyweirdos are precariously propped up on multiple crutches. This is just another one.
24 posted on 09/23/2003 6:10:21 AM PDT by upchuck (The Palis are a bunch of wackos with a 14th Century mentality and 20th Century toys. Kill 'em.)
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To: Pan_Yans Wife
Speaking as a former drunk, I can say the perfect hangover "cure" is plenty of water and asprin before bed. If you still have a hangover in the morning, try a Slurpee. (The liquid and sugar help). Of course, I haven't had a drink in five years, so what do I know.
25 posted on 09/23/2003 6:10:57 AM PDT by exile (Exile - proudly ticking off the Left since 1992)
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To: Pan_Yans Wife
I remember hearing something in the news about another drug that actually counteracted the effects of alcohol, effectively sobering someone after they get drunk. It seemed like all talk of it in the media went away when the mad mothers and "law enforcement" came out against it. Guess it would cut into their revenue stream if people could go out, have a few drinks, take a pill to sober up then drive home safely.
26 posted on 09/23/2003 6:17:17 AM PDT by Orangedog (Soccer-Moms are the biggest threat to your freedoms and the republic !)
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To: Orangedog
You are probably correct.
27 posted on 09/23/2003 6:22:03 AM PDT by Pan_Yans Wife ("Life isn't fair. It's fairer than death, is all.")
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To: Pan_Yans Wife

Its makers claim that it stops the body making an enzyme which turns alcohol into acetaldehyde, a toxic chemical which can damage tissues.

This sounds like it has positive benefits.

I'm not so sure about that... If the pill blocks the alcoholysis pathways, then, alcohol will not be processed and stick around in the body... Unless there's an alternative metabolic pathway for the alcohol to degenerate, it'll just sit around in the body (with the concomitant effects) until it's excreted.

Doesn't drinking water help a great deal, too?

Yes, if the body is slightly overhydrated, then the acetaldehyde will not be as concentrated and therefore its effects will be minimized until it's excreted.

28 posted on 09/23/2003 6:24:54 AM PDT by Chemist_Geek ("Drill, R&D, and conserve" should be our watchwords! Energy independence for America!)
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To: Pan_Yans Wife
Doesn't drinking water help a great deal, too?

Alcohol suppresses the hormone ADH (anti diuretic hormone). ADH prevents the body from losing fluid; suppression of this causes the body to increase fluid output via urine. That is why, when you drink a lot, you also urinate a lot. This can cause dehydration, which is why you feel so crappy the day after drinking. Drinking more water will ease the dehydration.

29 posted on 09/23/2003 6:26:02 AM PDT by Born Conservative ("Forgive your enemies, but never forget their names" - John F. Kennedy)
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To: exile
Cold turkey ?
30 posted on 09/23/2003 6:27:52 AM PDT by Eric in the Ozarks
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To: Chemist_Geek
Thank you.
31 posted on 09/23/2003 6:37:41 AM PDT by Pan_Yans Wife ("Life isn't fair. It's fairer than death, is all.")
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To: Pan_Yans Wife
Never mix the grape and the grain.

Stick to one thing if possible when you're drinking- ie, don't switch from beer to wine coolers to Jack and Coke.

Avoid overly sweet drinks- some berry wines and ciders will make the head split the next day.

Drink in moderation.

Drink plenty of water before going to bed and take aspirin as well.

Join the infantry- preferably the 82nd Airborne. Sometimes described as the most physically fit alcoholics in the world, they will teach you how to "drive on" even when you are hungover. Nothing like a good five mile run when you're busy puking your guts out.

32 posted on 09/23/2003 6:43:32 AM PDT by Prodigal Son
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To: Prodigal Son
Nothing like a good five mile run when you're busy puking your guts out.

You are speaking from experience?

33 posted on 09/23/2003 6:46:11 AM PDT by Pan_Yans Wife ("Life isn't fair. It's fairer than death, is all.")
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To: Pan_Yans Wife
So the idea is to spend a lot of money on this pill so you can spend a lot of money drinking at a bar so the drinking has no effect?
34 posted on 09/23/2003 6:55:33 AM PDT by Tribune7
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To: Tribune7
A fool and his money are easily parted? :)
35 posted on 09/23/2003 7:06:30 AM PDT by Pan_Yans Wife ("Life isn't fair. It's fairer than death, is all.")
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To: Pan_Yans Wife
Yes.
36 posted on 09/23/2003 7:42:16 AM PDT by Prodigal Son
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To: Pan_Yans Wife
A fool and his money were lucky to get together in the first place.
37 posted on 09/23/2003 7:47:59 AM PDT by Orangedog (Soccer-Moms are the biggest threat to your freedoms and the republic !)
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To: Orangedog
Good point! :)
38 posted on 09/23/2003 7:54:52 AM PDT by Pan_Yans Wife ("Life isn't fair. It's fairer than death, is all.")
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To: Chemist_Geek
If the pill blocks the alcoholysis pathways, then, alcohol will not be processed and stick around in the body... Unless there's an alternative metabolic pathway for the alcohol to degenerate, it'll just sit around in the body (with the concomitant effects) until it's excreted.

That's what I was wondering.
The article doesn't state what happens to the alcohol -- it just states that the process is "delayed."

"Delayed" until when?

39 posted on 09/23/2003 8:24:30 AM PDT by reformed_democrat
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To: Pan_Yans Wife
:-)
40 posted on 09/23/2003 9:14:19 AM PDT by Tribune7
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