There are two parts to this - what Roosevelt did and what the isolationists did. Lend-lease is a fine example of Roosevelt's efforts. His consistant support of Churchill another. His anti-Japanese measures a third. The isolationists weren't called that for nothing. I can't cite specific references in this time-frame but the writings of Churchill, William Shirer, and Barbara Tuchman should provide all the evidence.
2)Nobody anywhere in the world was successful at ending the Great Depression. Even now - 70 years later - people are still arguing about it and what was the proper course of action.
This is self-evident.
3)Roosevelt sent Jews back to Europe because that's what most of the public wanted - most prominent among them the same Conservative isolationists. Interestingly Jews in Stalin's Russia did much better than in most of Europe.
I've done some research on this. (Can't remember the name of the ship at this time). I've read the justifications and explanations. People didn't want the country flooded with refugees - especially of non-Christian, non north-western European origin. Roosevelt felt he couldn't admit Jews without opening the flood-gates. Anti-semitism was quite common among Americans of the time - especially so among conservative Republic isolationists (see Father Coughlin, for example).
4)Roosevelt rounded up the Japanese for one of three reasons; Either because they constituted a legitimate threat during wartime, because war-time prejudice endangered them, or because local California agricultural interests wanted their land. Take your choice.
This is common knowledge. I did some research on this in response to a thread on FR (because of the reparations issue). This is what I came up with. Roosevelt didn't just decide out of the blue to intern the Japanese. He was asked to do it by certain individuals who presented the first two reasons publicly. The third has been offered by various people at various times with various evidence.
There is now new evidence that these measures against the Japanese were instigated by a Stalinist in the U.S. Dept. of Treasury. An Assistant Secy. of the Treasury was instructed by Stalin's U.S. agents to embargo US steel scrap from the Japanese, in order to foment ill will between Japan and the US. This kept the Japanese preoccupied with the US, rather than their old enemy, the Russians. This embargo precipitated the attack on Pearl Harbor.
Harry Dexter White, the Soviet agent, stayed on in the Treasury Department for many years, as well as remained a communist. He had considerable involvement in the creation of the International Monetary Fund, the infamous IMF. You can see a photo of "Harry the Red", on the IMF's web site. They are quite proud of this mischievous little commie. One of FDR's many "New Dealers", that gave America the Raw Deal as often as they could.