of well informed men -- means we'll be needing folks with a good, solid, well-rounded education, a good selection of specialists in useful subjects, and a large dose of common sense all around.
who have been taught -- means we're gonna need folks who are well-informed and who prize knowledge, liberty, God, etc., and who are also able to teach; that is, to inspire the same in the rising generation
to know and prize -- means that folks will have to buckle down and learn, then go through whatever it takes to get to the place where they prize what they've learned
the rights which God has given them -- means that there are rights AND that they come from God; means that those rights are gonna be linked to moral behavior, reverence for the Almighty, his creations, and his creatures; means that once given they'll likely have to be cherished and defended because God seems not to be tolerant of those who take his gifts lightly
cannot be enslaved -- they will, however, be serving God; at peace with others who do the same, and interested in helping God extend these same benefits to those who do not enjoy them AND who are willing to do what it takes to get and keep them
Good idea to post that quote and ask for ideas