Certainly the concept of perceiving contains the notion that reality isn't mapped perfectly into our understanding. I believe some people have claimed that there is no reality, that it's all in our heads (why are they talking to us then?)
To me, life seems to work if you assume the universe is real, that our perceptions are fallible, and act accordingly. If someone tries to tell us we don't exist, guess we can pop them in the nose with impugnity.