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Cat Virus Tied to SARS (Hong Kong Travel Advisory Lifted)
NYTIMES ^ | May 23, 2003 | KEITH BRADSHER and THOMAS CRAMPTON

Posted on 05/23/2003 9:13:39 AM PDT by InShanghai

HONG KONG, May 23 — The World Health Organization today lifted its advisory against travel to Hong Kong and neighboring Guangdong Province in southern China, once the twin epicenters in a global outbreak of SARS, saying that the respiratory disease was being contained in both places.

The W.H.O.'s decision is the clearest sign yet that SARS is not spreading nearly as fast as once feared, although American officials have warned that it might show a resurgence next winter, the season when many other respiratory diseases are particularly prevalent.

The number of new cases reported daily in China has plunged in the last week. The disease has nearly disappeared after outbreaks in Singapore, Vietnam and Canada, while more than two dozen other countries have reported scattered cases that have not spread.

Taiwan is still having problems with severe acute respiratory syndrome, however, reporting 110 new cases in the last two days. But even there, officials are expressing confidence that they can bring the disease under control next month through better precautions in hospitals.

The W.H.O. left in place today its advisories against travel to Taiwan, Beijing and four Chinese provinces.

Today's lifting of the travel advisory coincided with an announcement by researchers here and in Shenzhen, just across the border in mainland China, that they had discovered a virus in a rare species of tree-dwelling cat that is virtually identical to the virus believed to cause SARS in humans.

Yuen Kwok-yung, a microbiologist at Hong Kong University, said that the corona virus had been found in the feces of masked palm civets, a nocturnal species found from Pakistan to Indonesia that is considered a delicacy in southern China. Some of the first known cases of SARS occurred last November among chefs and others in Guangdong Province involved in the preparation of wild game for expensive banquets.

A Chinese medical professor who had been treating infected patients brought the disease to Hong Kong, Asia's busiest transportation hub, in late February. Travelers from Hong Kong then carried the disease to Beijing, Taiwan, Singapore, Vietnam and Canada.

Masked palm civets have short fur that can be brown, orange, red or gray, with black bands on the head and feet. They eat mostly fruit, weigh up to 13 pounds and have bodies that grow up to two-and-a-half feet long, with tails of nearly equal length.

Judging from their activity and feeding habits, infected civets do not appear to feel any ill-effects from the virus. Only a small number of civets have been tested so far. Professor Yuen declined to say precisely how many, but most seemed to have the virus.

It is possible that the disease originated in another species and then spread to the civets, he said at a news conference this afternoon, while adding that he believed that the disease came to people from civets. While no tests have been done, it is also "theoretically possible" that household cats could become infected, as they are very similar biologically to civets, Professor Yuen added.

The raising and slaughter of civets and other exotic animals should be strictly regulated to prevent further outbreaks of SARS and possibly other new diseases, he said, while contending that a total ban on consumption of them could not succeed. "It is very difficult to stop a culture; it has been there for 5,000 years," he said.

Hong Kong reported just two new cases of SARS today, the eighth consecutive day when there have been fewer than five cases in the city.

The removal of Hong Kong from the travel advisory nonetheless came as a surprise. Almost up to the hour that the United Nations agency's decision was announced, Hong Kong officials were saying that they expected the advisory to remain in place for three more weeks because 146 people remain hospitalized here after being diagnosed with SARS.

The W.H.O. had previously said that it wanted to delay lifting the travel advisory until there were fewer than 60 active cases in hospitals here. Dr. Yeoh Eng-kiong, Hong Kong's secretary for health, welfare and food, said that local officials had just calculated that only 59 of the 146 people met the W.H.O.'s definition as active cases, while the rest were people who had already fought off SARS but remained in hospital because of other illnesses.

The disease outbreak and travel advisory have hit Hong Kong's economy badly. The autonomous Chinese territory, which has long served as a hub for travel around the region, has suffered mass cancellations on flights and in hotels.

The territory's financial secretary, Antony Leung, said that local officials would begin a campaign to revive tourism and business travel. "We will communicate to Hong Kong people and the world that Hong Kong is a safe place," he said.



TOPICS: Extended News; Front Page News; Miscellaneous
KEYWORDS: china; fipv; hongkong; sars; who
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Comment #21 Removed by Moderator

To: AD from SpringBay
Now that's stooping to a new low.
22 posted on 05/23/2003 10:32:24 AM PDT by dc-zoo
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To: InShanghai
Looks like a cross between a leopard and a racoon:
23 posted on 05/23/2003 11:18:54 AM PDT by TaxRelief
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Comment #24 Removed by Moderator

Comment #25 Removed by Moderator

To: InShanghai
I wonder, could the Chinese method of displaying live animals just outside the restaurant entrances have any connection to the spread of disease?
26 posted on 05/23/2003 11:23:36 AM PDT by azhenfud
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To: Dog Gone
"I suppose if a civet objected to being slaughtered and bit someone, it could transmit the virus."

Some restaurant patrons "pick" a live animal for slaughter/preparation. An infected live animal AT A RESTAURANT, exposed to the public, is asking for disaster.

27 posted on 05/23/2003 11:29:32 AM PDT by azhenfud
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To: DubyaDubyaDubya
Somebody had to say something like this.
28 posted on 05/23/2003 12:16:46 PM PDT by AD from SpringBay
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To: dc-zoo
You know you were thinking it.
29 posted on 05/23/2003 12:17:16 PM PDT by AD from SpringBay
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To: aristeides
You just know I'm not going to blame these poor little critters for SARS.

My money is still on Binny.

Although,they both have those big brown eyes........
30 posted on 05/23/2003 6:07:32 PM PDT by Betty Jo
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To: Betty Jo; Judith Anne; Mother Abigail; CathyRyan; per loin; Dog Gone; Petronski; InShanghai; ...
Interesting paragraphs from today's Washington Post story on this subject, Tests Indicate Animal Link for SARS : Mammals From China Market May Be Source of Human Infection :

The tests found a virus that appeared virtually identical to the SARS virus in saliva and feces of six catlike animals, known as masked palm civets. The researchers directly isolated virus from four of the animals and found pieces of genetic material from the microbe in two others. Tests also showed genetic evidence of the virus in feces of another animal, known as a raccoon dog, and an eighth animal, a Chinese ferret badger, had antibodies to the virus in its blood. None of the animals was sick.

A detailed genetic analysis of the virus isolated from the animals found it was identical to the SARS virus from human patients except that it lacked one sequence. The missing genetic material carries instructions for the production of a small protein, known as a peptide, and may have been the change that allowed the virus to jump to humans and then spread readily, Stohr said.

"The lack of this peptide may have helped the virus transmit efficiently from human to human," Stohr said. "Perhaps that missing piece of protein is just the trick, the little difference between a harmless animal virus and a human pathogen. That's a bit of speculation, but this is one hypothesis."

Masked palm civet belongs to Viverridae. Ferret badger belongs to Mustelidae. What kind of animal is a raccoon dog?

Let it be noted that domestic cats in this market tested did not show signs of infection with the virus in question.

31 posted on 05/24/2003 7:34:58 AM PDT by aristeides
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To: aristeides
Raccoon dogs (Nyctereutes procyonoides) are canids - but omnivorous - they eat fruit as well as meat.
http://www.canids.org/SPPACCTS/raccoond.htm

Civets are also omnivorous, as are ferret badgers. They are all reported to eat fruit.

Domestic cats - which apparently are not susceptible to SARS except transiently - are carnivores. They don't eat fruit.

Humans, which are susceptible to SARS, are also omnivores.

Interesting coincidence?
32 posted on 05/24/2003 8:06:38 AM PDT by CobaltBlue
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To: CobaltBlue
Carnivores have a shorter intestinal tract than omnivores, typically, because it takes longer to break fruit and grain down into particles that the body can use. This is one reason that cats can eat rotten meat without getting sick - it passes through too quickly to cause infection.
33 posted on 05/24/2003 8:08:19 AM PDT by CobaltBlue
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To: CobaltBlue
Herbivores and omnivores get Vitamin C from their diet. Carnivores make their own.

Herbivores and omnivores sweat, carnivores pant.

Herbivores and omnivores have alkaline saliva, carnivores have acid saliva, and their stomach acid is 20 times stronger than that of herbivores and omnivores.

Many more differences, these are just the most obvious.
34 posted on 05/24/2003 8:15:00 AM PDT by CobaltBlue
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To: CobaltBlue
Interesting observation. Pigs, of course, are omnivores.
35 posted on 05/24/2003 8:23:23 AM PDT by aristeides
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To: aristeides; Judith Anne; riri; blam; Dog Gone
Hmmm....peptides......Dr.Don Wiley.....

One of the dead microbiologists.

http://www.hhmi.org/communic/bulletin/oct95/wiley.htm

"By providing a precise picture of MHC-peptide binding,he has made the rational design of specific molecules for antiviral vaccines a reality."
36 posted on 05/24/2003 8:49:00 AM PDT by Betty Jo
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To: Betty Jo
I wonder if there's a way to find out whether any students of Dr. Wiley's are now working in China.
37 posted on 05/24/2003 8:55:58 AM PDT by aristeides
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To: Betty Jo
Peptides are the building blocks of proteins. Two amino or more amino acids linked together are peptides, and proteins are made of one or more polypeptides chains.

All living beings are composed largely of peptides, including immune cells, and viruses.
38 posted on 05/24/2003 9:00:32 AM PDT by CobaltBlue
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To: CobaltBlue; aristeides; riri; Judith Anne; blam; Dog Gone; Allan; Fred Mertz; CathyRyan
http://www.avibio.com/pr/pr169.html

http://www.lifesciencesinfo.com/tides

Peptides Oligonucleotides

"Oligonucleotide-and-Peptide-Based Therapeutics"

Don Wiley dead

Antisense

Hybridon ISIS IBIS

Mahfouz-Bin Laden-Camille Chebeir

DARPA

Sleeper cells

Old origional SEC documents

Pretend you are Columbo or Marc Furhman

39 posted on 05/24/2003 9:28:54 AM PDT by Betty Jo
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To: aristeides
You ask if any of Don Wileys students are working in China?

Maybe the question should be "Are the ideas of Don Wiley in the hands and heads of Bin Ladens mad scientists?"
40 posted on 05/24/2003 9:33:17 AM PDT by Betty Jo
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