I do not use Accutane in my practice and instead choose to refer all recalcitrant acne cases to dermatologists in our area. I have little first hand experience with this particular medication because I choose not to write it often.
Quoting the package insert:
"Pediatric patients and their caregivers should be informed that approximately 29% (104/358) of pediatric patients treated with Accutane devleoped back pain. Back pain was severe in 13.5% (14/104) of the cases and occurred at a higher frequency in female than male patients.
Arthalgias were experienced in 22% (79/358) of pediatric patients.
Arthralgias were severe in 7.6% (6/79) of patients. Appropriate evaluation of the musculoskeletal system should be done in patients who present with these symptoms during or after a course of Accutane. Consideration should be given to discontinuation of Accutane if any significant abnormality is found.