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To: EternalHope
The SARS-associated Coronavirus Complete Genome Sequence -------------------------------------------------------- The following resources are now available from the Genome Sciences Centre, SARS-associated virus genome sequencing project, at the British Columbia Centre for Disease Control and the National Microbiology Laboratory, Winnipeg.

(1) The current Genome Shotgun Data are available for download. The format is raw sequence reads in Fasta format, not vector or quality clipped.

(2) Comparison to other members of the order _Nidovirales_ [which includes the families _Coronaviridae_ and _Arteriviridae_ - Mod.CP]]. These images were generated by the Sockeye genome viewer, developed at the Genome Sciences Centre. The images show the comparison of the sequence of the TOR2 isolate [i.e. a virus isolated from a Canadian patient] to the sequence of other related members of the order _Nidobvirales_. The tracks show Blast comparison to (1) avian infectious bronchitis virus, (2) bovine coronavirus,

(3) human coronavirus 229E,

(4) murine hepatitis virus, (

5) porcine epidemic diarrhea virus,

(6) transmissible gastroenteritis virus. An annotated image is also available.

http://www.promedmail.org/pls/askus/f?p=2400:1001:41129919313081845::NO::F2400_P1001_BACK_PAGE,F2400_P1001_PUB_MAIL_ID:1000,21266

3 posted on 04/14/2003 4:09:51 PM PDT by CathyRyan
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To: CathyRyan
Also from Promed:

It should be noted that analysis of sequences from 3 different regions of the genome confirm the initial observation that the Urbani strain of the SARS-associated coronavirus is distinct from all previously recognized coronaviruses and sequence studies are not likely to identify a source for this novel coronavirus.

and

The genome appears to be that of a "completely new" coronavirus unrelated to any known human or animal viruses, a scientist at the Canadian agency said. a competing United States team at the Centers for Disease Control and Prevention in Atlanta is reaching the same conclusion, and scientists from both teams said the virus's startling novelty could make it harder to trace what animal or bird it came from, if it did jump from another species.

4 posted on 04/14/2003 4:32:59 PM PDT by EternalHope
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