Future missions (if ever continued) should include tile repair kits. Autos have been equipped with spare tires for nearly a century. But autos have four identical tires. All the tiles are different. Though epoxies will cure in vacuum, and were used as ablation shields in the early Mercury and Gemini programs, so, Yes, they could make "Blowout" kits. But someone would have to go outside to use it.
Not me, I hate heights.