BZZZZZZZZZZZZZZZ the hornets are flying.
We all have our favorites, but when it comes to concealed carry, there are many factors to be considered to determine what is optimal, and as those conditions change, so do the selection. For example, as much as I like my Sig P229 in .40 S&W, I'm not going to carry that here in Florida in the summer when wearing anything heavier than shorts and a tank-top will quickly reduce one to a puddle of perspiration. During the winter, though, my Sig goes everywhere I do, no problem.
With the developments in ammunition over the last decade, just about anything, even a .22lr (check out CCI's "Velocitor"), will work when you quickly dump the entire magazine into the goblin at five yards. At the very least, it will screw up the BG long enough for you to beat a hasty retreat!