[Nov3]

The lawsuit says that a human enzyme dubbed CYP2D6 normally metabolizes or breaks down Prozac and similar drugs in the body, but fails to do so in a minority of people. In their bodies, the active ingredient in Prozac builds up to high levels, putting them at risk of violence and suicide, the lawsuit says.

I don't know about all that but the new Eli Lilly commercial that says you might be Bipolar and does not attempt to market any specific drug is telling. They are trying to lay the groundwork to blame the cases of mania, mayhem, and murder at the feet of an unreported manic problem. It is strange that these people are just depressed and have never had manic symptoms before they started the SSRI's? When they stop the SSRI's they don't have any manic symptoms? Only when they are on the drug do they have manic symptoms. It must be the person is manic and not being caused by the drug. Logical right?

I would love to see what Eli-Lilly documents the plaintiffs lawyers got during discovery. I will bet those documents are covered by a major non-disclosure agreement.

[Nov3]

Fyi

[matthew_the_brain]

Good, I am glad she is getting Lily to pay up for peddling this poison.

[Rain-maker]

One pill makes you larger,
And one pill makes you small,
And the ones that Eli Lilly gives you,
Makes you delirious to all,
Go ask Alice,
When she's getting ready to fall...

[trebb]

I agree that the drug companies are not always on the up and up, but I'd like to see what:
1. The doctors use as a basis for prescribing the drugs.
2. What the tendency of the person was BEFORE taking the drug.
3. Whether there is any indication that the person abused the drug.

[technochick99]

I don't know about all that but the new Eli Lilly commercial that says you might be Bipolar and does not attempt to market any specific drug is telling.

When doctors prescribe medications, they typically only have a person's self reporting to go on. This makes people who suffer from depression take a moment and reflect on their overall behavior, thus giving themselves a chance to give a more accurate report.

[Fred Mertz]

Lilly said in a statement that it "made a business decision to settle ... for factors completely unrelated to the safety and efficacy of Prozac," The Indianapolis Star reported in a story Saturday.

Yeah, right.

[Petronski]

Prozac for weight loss? I think that's off-label.

[Petronski]

For the vast majority of patients using SSRIs, the effects can be life-saving. For a small minority, the 'crawl-out-of-your-skin' mania can result. I think Lilly might have cheaped-out on the research re: a "human enzyme dubbed CYP2D6 [which] normally metabolizes or breaks down Prozac and similar drugs in the body, but fails to do so in a minority of people."

It seems people deficient in CYP2D6 can't handle Prozac.