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Scripps scientists link chemical in tobacco with onset of diseases
UNION-TRIBUNE ^ | 29 October 2002 | Bruce Lieberman

Posted on 10/29/2002 1:52:58 PM PST by Asmodeus

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1 posted on 10/29/2002 1:52:58 PM PST by Asmodeus
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To: Goldustwoman
ping
2 posted on 10/29/2002 1:57:43 PM PST by Ff--150
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To: Asmodeus
This stuff is safer than mothers milk doncha know ? In fact some smokers live to be 100 years old and never sick a day in there lives. We have far more serious problems to lick like fatty foods than to waste our time on tobacco use.
3 posted on 10/29/2002 2:00:21 PM PST by VRWC_minion
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To: Asmodeus
I wonder how long it took em to dream up this phoney excuse to scare people?
4 posted on 10/29/2002 2:41:45 PM PST by INSENSITIVE GUY
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To: INSENSITIVE GUY
You serious?
5 posted on 10/29/2002 2:46:48 PM PST by El Sordo
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To: Asmodeus
The smokers are never gonna believe this. The FR smokers are hardcore.
6 posted on 10/29/2002 5:11:49 PM PST by Ditter
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To: Asmodeus
Thanks for the post, Asmodeus. Education is the key to preventing tobacco addiction.
7 posted on 10/29/2002 5:52:37 PM PST by solzhenitsyn
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To: Asmodeus
Well, there's worse things out there. It's better than AIDs, yet they aren't doing much to stop that. It's a "deathstyle choice" that kills much faster than tobacco.
Everybodies gotta go sometime. Some faster than others.
8 posted on 10/29/2002 5:56:45 PM PST by concerned about politics
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To: INSENSITIVE GUY
I wonder how long it took em to dream up this phoney excuse to scare people?

I read a study that said the sun did the same thing.
Maybe the Nico-Nazis paid for this study, too.
I'd like to know who paid for the study before taking it as fact.
I don't even smoke. But usually, these studies are paid for by people with an agenda. The results could be fabricated for profit.
I wouldn't consider this breaking news. Possible propaganda, yes.

9 posted on 10/29/2002 6:02:33 PM PST by concerned about politics
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To: concerned about politics
"Maybe the Nico-Nazis paid for this study, too. I'd like to know who paid for the study before taking it as fact. I don't even smoke. But usually, these studies are paid for by people with an agenda. The results could be fabricated for profit."

The study was supported by the Skaggs Institute, which was funded by a $100M gift from philanthropists Samuel and Aline Skaggs. You can read all about it here:

http://garbanzo.scripps.edu/nmrgrp/skaggs/utrib.skaggs.2.html

You're right, those "Nico-Nazis" do have an agenda. It's saving human lives. Pretty sinister stuff. Unlike those nice people who made millions by telling us for decades that tobacco was safe, and who then told us that the evidence re the health risks of tobacco was ambiguous (when they knew that to be untrue), and who are even now convincing smokers that the same smoke that causes cancer in a smoker's lungs is absolutely safe when it enters the lungs of a non-smoker. Now, those guys you can trust -- no agenda there, and no profit motive.

10 posted on 10/29/2002 7:01:27 PM PST by solzhenitsyn
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To: Asmodeus
Gosh, before smoking was invented people must have lived much, much longer! Or maybe not.

;^?

11 posted on 10/29/2002 7:12:06 PM PST by Fifth Business
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To: Asmodeus
Gosh, before smoking was invented people must have lived much, much longer! Or maybe not.

;^?

12 posted on 10/29/2002 7:12:35 PM PST by Fifth Business
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To: Fifth Business
So much for internal server errors.
13 posted on 10/29/2002 7:15:13 PM PST by Fifth Business
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To: Asmodeus
testing the blood of 20 smokers and nonsmokers

Not exactly a broad sampling, eh? It doesn't mention the age or the physical condition the people... their environment....whatever. Where they truck drivers? Coal miners? What types of medications and pollution have they been exposed to in their lifetime? This is tripe.

14 posted on 10/29/2002 7:21:04 PM PST by LaineyDee
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To: Asmodeus
Janda and Dickerson, testing the blood of 20 smokers and nonsmokers...

Wow, a comprehensive study like this erases all doubt in the public's mind.

I quit!

Not.

15 posted on 10/29/2002 7:37:28 PM PST by metesky
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To: concerned about politics
"I read a study that said the sun did the same thing. Maybe the Nico-Nazis paid for this study, too. "

These people are ate up with this $hit. I went to a neurosurgeon the other day for my back. First time I had been to this doctor, also the last. I had been waiting for about 20 minutes in the examination room. The doctor opened the door and stood in the doorway to talk to me. He never sat down and never examined me in any way. He wore a bandana around his head like a pirate. This is true. The first words out of his mouth were asking me , if I was a smoker. When I answered yes, he told me I had to quit or he would not be my doctor. I nodded. He ordered a MRI for me and charged me $278.00. I had the MRI done, but will not go back to the A-hole for his diagnosis. This is why I say these people are really ate up. Not only is he ate up, he is also a thief.

16 posted on 10/29/2002 7:38:23 PM PST by auggy
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To: Ditter
The smokers are never gonna believe this. The FR smokers are hardcore.

No, Ditter. The smokers will believe the study - just not the spin put on it. Typically, smokers know far more about the subject (science and politics) than non-smokers do. So, when anti-smoking nazis like Bloomberg and special interest groups like pharmaceutical companies masquerading as "research institutes" quote "science" to back them up, we know enough to be plenty skeptical.

So, let's look at this study and its results.

The main problem identified here is supposedly the "advanced glycation endproducts" or AGE's.

Now, glycation is the non-enzymatic glycosylation of proteins, nucleotides and lipids by saccharide derivatives. But, you need to realise that glycation is an unavoidable aspect of physiological metabolism (though minor in most healthy people). Even "breathairians" glycate all the time!!

Glycation of proteins leads to covalent crosslinking and abnormal structural stabilization of extracellular matrix proteins, and recognition by specific receptors ("AGE receptors") and consequent cell activation.

The theory (and I stress the word theory) is that glycation-mediated protein crosslinking and cell activation in cell dysfunction is associated with the advent of certain diseases, such as diabetes, vascular disease, Alzheimer's, cancer and aging.

Now, normally AGE's are cleared through the kidneys as a normal part of the body's metabolism. It is only when the body's renal functions start to deteriorate (with age or disease) or when the AGE levels are too high for the kidneys to efficiently clear them that theoretical problems potentially arise in some people.

This press release is high on spin and low on details.

For example, there are numerous types of AGE's. It does not state which AGE's we are talking about here. In all cases, the "dose is the poison" and even too much water can kill you. This press release does not include any information on the rate at which AGE's in smokers' blood is elevated above normal. That is, are AGE levels in smokers' systems sufficiently elevated that the kidneys cannot clear them and, if so, are the levels sufficiently elevated to cause disease?

Which, of course, begs the question as to what level of AGE's causes disease? How do AGE's in smokers' blood compare with, say, a diabetic, or someone with cancer, or Alzheimer's?

Answer: they don't know, because they didn't look for that. All they could say was that smokers had higher levels of nicotine in their blood, therefore higher levels of nornicotine, and seeing as the body breaks down nornicotine by glycation, smokers had elevated levels of AGE's in their bodies - genius! Give that man a grant!

To throw even more cold water on this "study", one of the authors is a mere PhD student, who makes an incredibly stupid statement in the Scripps Institute's press release that:-

"These advanced glycation endproducts are not supposed to be [present in your body] naturally," says Tobin Dickerson, a Ph.D. student in TSRI's Kellogg School of Science and Technology.

As I mentioned above, AGE's are most certainly supposed to be present in your body naturally - the only people who don't have them are those who have been cremated!

So, these are some of the reasons why smokers on FR are so hardcore - no doubt this "study" will be added to the "weight of evidence" against tobacco, when in fact it is no evidence at all!!

And this is our problem. Smokers on FR will not claim that smoking is risk or harm free (active smoking, that is - don't get me started on second-hand smoke). However, the mass hysteria generated by garbage studies like this one has been used to harass us, steal from us, banish us and generally discriminate against us in every imaginable way.

All this time, effort and money spent to demonise us has most certainly hardened us and turned us into cynics. As any psychologist could have told you, our response to this abuse is as natural as glycation!

17 posted on 10/29/2002 8:30:51 PM PST by I'm_With_Orwell
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To: I'm_With_Orwell
Yep, I knew you weren't going to believe it. Most of the smokers here aren't as scientific as you, they say "my grandaddy smoked till he was 90 & died in his sleep" or some such such claptrap.
We had one of those in our family, Uncle Charlie smoked his whole life & lived to be 91. The rest of the smokers (& there were a whole lot in mine & my husbands combined families) died in their 50's or 60's. They ALL died painfully & slowly of smoking related diseases.
So you guys keep hiding your heads in the sand & coming up only to smoke. I've done my own study & I came up with the theory that smoking is bad for you & causes illness that you otherwise wouldn't have to deal with for many more years. Disbelieve that if you want to.
18 posted on 10/30/2002 1:16:46 AM PST by Ditter
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To: Ditter
My mom's death is at least partially attributable to her smoking addiction. Of course, she told me how her grandma lived into her 90s', and smoked a corncob pipe! But I have no doubt that the length and quality of her life would have benefitted from not smoking.

Glycation contributes to stiff organs, veins, eye conditions and wrinkled skin. It is a natural process in aging. One of the chief AGEs culprits is sugar, esp. the "natural" fructose one found in fruit! Of course, I still eat fruits and avoid cigarettes. And I also take various supplements to inhibit (and perhaps reverse) AGEs, (with the amino acid l-carnosine being one of the important supplements).

19 posted on 10/30/2002 7:37:59 AM PST by pollwatcher
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To: pollwatcher
I have heard the word glycation before. My nextdoor neighbor is an M.D. She was talking about her sister-in-law who is a heavy smoker. Even tho the woman is not old she is beginning to exhibit some physical symptoms attributed to very heavy smoking. She mentioned her skin & her fingernails. I got the impression her nails were becoming deformed. I wish I had listened more closely.
20 posted on 10/30/2002 11:26:46 AM PST by Ditter
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