[SkyRat]

Would matter/anti-matter reactions create energy?

It would relase a lot of energy. A matter <-> anti-matter reaction is 100% mass to energy transformation. A nuclear bomb on the other hand only transforms around 8% of it's mass.


Would it be safer than nuclear power?

No. Any contact between normal and anti matter is big firework. The only way to contain antimatter is by some sort of magnetic trap.

[Poohbah]

IIRC, even the fabled W-88 warhead only releases 0.5% of its mass as energy.

[Terriergal]

The only way to contain antimatter is by some sort of magnetic trap.

And this would isolate antimatter from matter... how?