I find it hard to believe that someone buying 22s in boxes of 500 could also claim that 100 rounds a Year is a reasonable usage rate. And no, we're not talking "tens of dollars" but "tens of thousands".
It's reasonable for what I do. About once every 5 years I buy a brick of 22s. I shoot them infrequently and just to eliminate any trace of hiccups that shooting the big bore pistols induces.