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To: sunnshine2
He is wrong. Human genes are counted at 58,000, and other scientists have counted more then 70,000 and counting

It is notable that the opinions expressed in the following links are not as definite as yours.

Link 1
Link 2
Link 3
Link 4
And I like the comment contained in the following where a member of the OSU team hedges on its count. IOW-- "I strongly suspect our numbers are high"

Link 5
"Some researchers are unsettled by the certainty with which the Human Genome Consortium is presenting its lower gene count," said Fred Wright of Ohio State University. "In my view, the final number of genes - when it is known - will lie somewhere between their high of 40,000 and our value of 70,000."

109 posted on 03/12/2002 1:50:29 PM PST by AndrewC
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To: All
Just a quick note - and again, I apologize for being able to give this the time it really is due - much of the confusion in this issue is resulting from a matter of terminology. DNA codes for proteins, but genes (and combinations of them) code for traits. The latter constitute a mental model much older than molecular biology - Gregor Mendel and all that, mid-18th century if memory serves me correctly. A gene to him was whatever mysterious factor it was that coded for a trait such as wrinkly leaves on a pea plant.

It isn't much more now. We know that DNA codes for proteins and we know that proteins are involved in the expressions of traits. What we don't know is how many proteins are involved per trait - but it's looking like it varies from trait to trait, which makes a lot of common sense. The assertion that it was a one-to-one ratio was really more one of science popularization than real science - it makes it easy to visualize, but it's a major oversimplification to which science popularization is prone. But I don't think any working molecular biologist has been proceeding under that assumption for decades if ever.

The Human Genome Project's actual product was a listing of DNA sequences, and nothing more. There are a number of crude methods of estimating protein expression from this (simply enumerating stop codons is one) but no precise one, and no method at all of estimating traits, hence genes. Anyone who ever said it could do that was either misunderstanding the process or deliberately misrepresenting it. Without pointing any fingers I will observe that science journalists are prone to the first and scientists hungry for grant money to the second. Of course, the same is true of "debunkers."

111 posted on 03/12/2002 2:16:39 PM PST by Billthedrill
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To: AndrewC
Not only are the scientists unable to say exactly how many genes there are, but the two companies who separately researched the human genome, do not agree on which part of the genome are genes.
122 posted on 03/12/2002 5:24:17 PM PST by gore3000
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