>>But my point is, if $100 was the going rate for an FDA-approved vaccine, I'd do it, for me and my wife<<
Under current FDA policies, adopted in the 1990s, there will never be an "FDA approved" smallpox vaccine.
My advice? :
Take it anyway.
Ok. Scratch the "FDA-approved" and replace it with something along the lines of: "generally accepted safe". And I'll be the judge, for my own situation, of what is and isn't safe. For example, I wouldn't go to Mexico to get this shot.