My kinda gal.
Carol, leave the 9mms alone and get the .45 ACP model of whatever you prefer. The Sig you tested is going to be hard to beat, I think. Sigs have the best stock sight-picture and natural 'pointability' out of the box over any other pistol.
Like hd5574, I have a M1911-A1 Government clone. It's a 1990-vintage Springfield Armory with no modifications on it except for a 3.5 pound trigger and the 1911 original-style (straight-backed) mainspring housing.
However, if I were to buy another pistol now to *replace* my 1911-A1, it would certainly be a Sig-Sauer .45 ACP.
As far as throwing knives are concerned, I can't recommend them. I *do* have some well-balanced throwing bricks for sale that are quite a lot more effective.
Become and expert with them, and 'one-shot-stops' are commonplace, particularly from behind.
I do use an oversize slide release on all my 45's as with my small hands I have found that much easier. I tried some beautiful smooth rosewood grips but found that they made the gun slip in my hand and pulled my shots to the left, so I put the old checkered ones back on.(sob) I am small about 5'2" and 100 lbs so if I can handle a 45 most people can.
I have been shooting for well over 40 years, the last ten of those mostly point shooting and have tried most of caliburs (22,25,32,38,380,357,40 in a mix of semis and wheel guns) but 45 will be always be my baby. The only wheel gun I ever found that truly fits my little hands in the Ruger Bearcat and that just doesn't have enought knock down punch. I have found that all of the Colt's based on Browning's Designs are great for women with small hands.