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I respect your views and would defend your views, however I know that in the dark being awaken from a deep sleep, I wouldn't have the accuracy to pull off a nice shot like at a range. This is the reason I choose a 12ga. I like squirrel hunting with a .177 spring action pellet rifle and can accomplish nice clean head shots when wide awake. Most people aren't their sharpest coming out of a deep sleep (and eyes getting use to the light). So If you feel safe with a .22 and can shoot it after waking up, Then I respect your ability as a hunter and your choice for home protection. However, most people who own guns for home protection are not expert hunters. They may require a firearm that is a little more forgiving. We may disagree, but I defend your decision and position !!

I agree with what you are saying. The Shotgun is the way to go in the case where you need some spread. If you are awake and can get a good shot, any of the calibers discussed here will do the job. Speaking of .17 caliber, have you ever heard of the .17 remington bee? 4040 feet per second.