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"Read the context of that. Paul was railing against the judaizers who had returned to the old ways despite his remonstrance. It can't be taken as a general statement that no repentance is possible for sinners."

Just go on and on with stuff. You've got scripture staring you in the face.

Hebrews 6:4-6
"For in the case of those who have once been enlightened and have tasted of the heavenly gift and have been made partakers of the Holy Spirit, and have tasted the good word of God and the powers of the age to come, and then have fallen away, it is impossible to renew them again to repentance, since they again crucify to themselves the Son of God and put Him to open shame."

JM