The inquisition was in the 1490s. About 2 decades before the Reformation., which brought about Protestantism.
The Spanish inquisition lasted until the 1800’s. Originally it was against Jews and Muslims, but then was against protestants.
Hilarious
The first Inquisition was against the Catharists in Southern France in the 1180’s. The result was the Albigensian massacre (”Kill them all. God will recognize his own”).
The Spanish Inquisition that you are referring to started in the 1470s and continued for well over four centuries until ended by Bonaparte in 1808. Here in “the New World”, it was started up in Mexico in 1570, well over a century after you claim it occurred:
“As Spain expanded into the Americas, so did the Inquisition, established in Mexico in 1570. In 1574, Lutherans were burned at the stake there, and the Inquisition came to Peru, where Protestants were likewise tortured and burned alive”
The United States and their Constitution was formed two centuries later by a populace that was 98% Protestant and utterly opposed to continuing oppression of the Roman Catholic “church” and its bludgeoning of anyone who dared question it. Thus the First Amendment and the Establishment Clause.
You can read all this at even a trivial site like History.com:
https://www.history.com/topics/religion/inquisition
They did an OK job. But they didn’t go into other things like the fact that the very first landing of Protestants in Florida - the Huguenot at St. Augustine - was occasioned by their massacre at Matanzas under the orders of the Spanish Naval commander in 1565. For the crime of being Protestants.
https://www.nps.gov/foma/learn/historyculture/the_massacre.htm
It is for this reason that the influx of Catholics into this country in large numbers in the 1840s was regarded with dread and revulsion by the almost 100% Protestant populace who had been the victims of these atrocities for 3 1/2 centuries.
So your timeline is rather ridiculousy constrained. The Spanish Catholics were the most vehement of the Inquisitors but not the only ones. It’s maybe understandable in the face of the Muslims, but to equate Lutherans with Muslims is ludicrous. And to let them settle in this country which was founded by and once almost monotonically Protestant is, um...insane.
At least for us WASPs.