This article says syphilis, gonorrhea and chlamydia have developed antibiotic resistant Versions:
https://www.webmd.com/sexual-conditions/antibiotic-resistant-std-faq
I remember the warnings around 1975 that a new strain of clap from Asia had invaded the US in Salt Lake City of all places!
It required a different antibiotic to stop it.
Decades ago I read the book EVERYTHING YOU WANTED TO KNOW ABOUT SEX (BUT WERE AFRAID TO ASK) listed some other forms of VD that were absolutely horrible!
Now that California has basically made it legal women soliciting on the streets, maybe they better go back to the old military method of issuing a number tag to each one. Then on the radio or TV they can have a broadcast of all the women who were tested positive. “Here are your numbers for today...27, 82, 16...” and so forth.