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World-first vaccine that fights off range of fungal infections is 100% effective at preventing severe disease in early study
MAILONLINE ^ | 7 February 2023

Posted on 02/07/2023 2:46:15 PM PST by dennisw

The World Health Organization warns fungal infections are becoming a 'major threat' to public health and more common worldwide as the changing climate makes environments more suitable for them.

As hit show The Last of Us heightens fungal fears

Researchers developed a vaccine highly effective against fungal infections The NXT-2 shot prevented severe infection in all animals it was tested on

Scientists have developed a first-of-its-kind vaccine to prevent severe symptoms from hard-to-treat fungal infections.

In a study on animals, the shot - made by researchers from the University of Georgia (UGA) - worked against the three most common families of fungi that cause disease in people.

The vaccine is known as 'pan-fungal' because it targets an enzyme shared by all three strains, which collectively cause around 3,500 deaths and 50,000 hospitalizations annually in the US.

Increased attention has been placed on fungal infections because of the hit HBO show 'The Last of Us', which sees infected people transform into zombies.

While that is far from reality, data from the Centers for Disease Control and Prevention (CDC) shows fungal infections already caused 7,000 deaths in the US - and 1.5million worldwide, in 2021.

The vaccine, called NXT-2, works by providing the body with antibodies that can fight off infections caused by three species of fungus: Aspergillus, Candida and Pneumocystis.

The shot was 100 percent effective at preventing serious infection in monkeys and mice that were immune suppressed and exposed to a fatal amount of fungi.

Researchers say that plans for a human trial are now underway.

'There's a significant unmet clinical need for this kind of prevention and also treatment, particularly among immunocompromised individuals,' Dr Karen Norris, a veterinary medicine professor at UGA

'The patient population at risk for invasive fungal infections has increased significantly over the last several years.'

(Excerpt) Read more at dailymail.co.uk ...


TOPICS: Culture/Society; News/Current Events; Unclassified
KEYWORDS: fungal; infection

1 posted on 02/07/2023 2:46:15 PM PST by dennisw
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To: dennisw

At least it seems there is some proper testing going on. Before this stuff is rolled out, to be injected into everyone’s arms.


2 posted on 02/07/2023 2:47:34 PM PST by dennisw ("You don't have to like it. You just have to do it")
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To: dennisw

just in time to prevent the last of us from actually happening!

;)


3 posted on 02/07/2023 2:50:45 PM PST by TexasFreeper2009
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To: dennisw

Well, if it’s not Pfizer, it could quite possibly be an actual vaccine. That works.


4 posted on 02/07/2023 2:54:35 PM PST by Da Coyote
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To: dennisw

Thanks to the BS we have been fed the past 3 years does ANYONE trust anything about vaccines, anything from the CDC,
or anything from pharmaceutical companies?

It could be the greatest vaccine ever but who trusts them? Well, besides the sheep that still do...


5 posted on 02/07/2023 2:55:14 PM PST by Organic Panic (Democrats. Memories as short as Joe Biden's eyes)
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To: dennisw

Finally, a true cure for toenail fungus!


6 posted on 02/07/2023 2:58:02 PM PST by Dr. Sivana (But yet the Son of man, when he cometh, shall he find, think you, faith on earth? (Luke 18:8))
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To: dennisw
M A R K E T I N G.

And using public dollars and major media to do it. No need to pay for advertising anymore. The governments are now servants to the marketing.... Take your jab. Take your nest jab. Next. And next and,,,,

7 posted on 02/07/2023 3:01:24 PM PST by Worldtraveler once upon a time (Degrow government)
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To: dennisw

Too bad the credibility got trashed by Fauci and Pfizer.


8 posted on 02/07/2023 3:05:16 PM PST by blackdog ((Z28.310) Forget "Global Warming", new grants are for "Galaxy Dimming")
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To: dennisw

Lol, I would not believe the WHO if on a sunny, cloudless day they told me the sun was shining.


9 posted on 02/07/2023 3:05:43 PM PST by Cen-Tejas
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To: dennisw

Increased attention has been placed on fungal infections because of the hit HBO show ‘The Last of Us’, which sees infected people transform into zombies.

Something seriously wrong with this.


10 posted on 02/07/2023 3:10:42 PM PST by ifinnegan (Democrats kill babies and harvest their organs to sell)
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To: dennisw

Two Words: HUMAN COMPOSTING


11 posted on 02/07/2023 3:12:44 PM PST by Jan_Sobieski (Sanctification)
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To: dennisw
Pneumocystis, Aspergillus, and Candida are the three fungi mentioned. Aspergillus niger and fumigatus are two of the bad guys causing apergillosis, a disease similar to pneumonia. Candida auris is a pernicious fungus and almost resistant to all antibiotics.
12 posted on 02/07/2023 3:30:15 PM PST by Fungi
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To: dennisw

>>At least it seems there is some proper testing going on.

In research published in PNAS Nexus, researchers gathered data from 103 mice and 25 monkeys.

They tested four different vaccine candidates against Aspergillus, Candida and Pneumocystis.

In 20 of the mice and two monkeys, they vaccinated them but did not expose them to fungus - to determine the safety of the vaccines.

The others were vaccinated and had their immune system suppressed by drugs before being exposed to a fatal fungus dose.

This is done to simulate how effective the vaccine would be in an immunocompromised person who is most at risk of severe illness.

The NXT-2 shot was the only shot to effectively prevent severe infection against all three fungi in every animal it was tested against.

The shot also did not show any significant adverse side effects to the 12 animals that received it and were not exposed to the deadly disease.


13 posted on 02/07/2023 3:45:17 PM PST by FarCenter
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To: dennisw

I will trust by body to deal with this...............


14 posted on 02/07/2023 3:47:06 PM PST by Osage Orange
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To: All

Probably basically Ivermectin, changed just enough to get a new patent.


15 posted on 02/07/2023 4:03:34 PM PST by LegendHasIt
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To: dennisw
At least it seems there is some proper testing going on. Before this stuff is rolled out, to be injected into everyone’s arms.

Now all we need is a fungal infection crisis.

16 posted on 02/07/2023 4:15:47 PM PST by usurper
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To: dennisw

https://news.yahoo.com/dangerous-fungal-illness-rapidly-spreading-182156354.html?guccounter=1&guce_referrer=aHR0cHM6Ly93d3cuYmluZy5jb20v&guce_referrer_sig=AQAAAE6it6liZviHkDuHItTBzkpD_9uuQcAnAw6a6-4G5_9sglTGYB9MoAlpvGvtvMkq2uqHSsJgrfViiLIOj20dh3E7xXzIGrx0NfDdSCGud-Wod1alUb5tD87MR-zdqOa8nmaLAVL8L4wtoJzauYHGcnQ71l80zITj6Uq2CADIcO0I

SAN FRANCISCO – Doctors are warning of a dangerous fungal illness rapidly spreading across the country, especially affecting those living or visiting the California and Arizona areas.


17 posted on 02/07/2023 4:19:00 PM PST by PeterPrinciple (Thinking Caps are no longer being issued but there must be a warehouse full of them somewhere.)
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To: dennisw

I eat mushrooms, so I have natural immunity.


18 posted on 02/07/2023 4:23:08 PM PST by AlaskaErik (There are three kinds of rats: Rats, Damned Rats, and DemocRats.)
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To: dennisw

No longer interested in anything Big Pharma is pushing!

Don’t trust them to NOT kill me!


19 posted on 02/07/2023 6:11:47 PM PST by SoConPubbie (Mitt and Obama: They're the same poison, just a different potency)
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To: Da Coyote

The WHO is totally unbelievable. Here we go again. Fool me once, shame on you. Fool me twice, shame on me.


20 posted on 02/08/2023 3:23:47 AM PST by Machavelli (True God)
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