Up to that point that raid cost the loss of over 600 crew (killed\wounded or captured) members in a single raid, later raids directly into the heart of Germany had higher costs in planes and crews. Operation Tidal Wave made many in upper command question the use of Daylight Bombing due to casualties. It took 6 months of reduced bombing sorties to recover from the loss of equipment and trained crew replacement.
Another detailed account of the Ploesti Raid can be found here: