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World's first woman is 'cured' of HIV after receiving rare - but dangerous - stem cell treatment to fight both virus and cancer
dai ^

Posted on 02/15/2022 12:00:42 PM PST by algore

For the first time ever, a woman has been cured of HIV.

A woman dubbed the 'New York patient' by scientists at New York-Presbyterian Weill Cornell Medical Center in New York City has defeated the virus after receiving a rare, but dangerous, stem-cell treatment.

She is the fourth person to ever be cured of HIV - the previous three are all men - and experts have found two cases of women somehow beating the virus naturally.

The woman was also a cancer patient, and received a treatment meant to combat both diseases at once - but is also so risky that it has been deemed 'unethical' to use it on people who do not have a late-stage cancer diagnosis.

In order to perform this treatment, doctors must first find a donor who has a rare mutation that makes them resistant to the virus.

Experts tell NBC that people who have this mutation are usually northern European, and even then only one percent of that population has it.

Doctors then perform a 'haploidentical cord transplantation' which uses umbilical cord blood and bone marrow from the donor.

The cord blood helps fight blood based cancers - like the leukemia the woman was suffering from, while the bone marrow provides stem cells to the body.

Because cord blood is usually not as effective for adults as it is children, the stem-cell transplantation can help boost its effectiveness.

Because this stem cell treatment can often result in death for the patient, experts will not use it on a health person who can manage their HIV through normal methods.

(Excerpt) Read more at dailymail.co.uk ...


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Sounds Expensive.
1 posted on 02/15/2022 12:00:42 PM PST by algore
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To: algore

“World’s first woman”

Eve? She’s getting a bit long in the tooth, I think.


2 posted on 02/15/2022 12:02:09 PM PST by rightwingcrazy (;-,)
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To: algore

They’re “cured,” until they’re not.

How many false alarms have we heard? Even the “Berlin patient” Timothy Brown died relatively young from the effects of treatment.


3 posted on 02/15/2022 12:03:18 PM PST by fwdude (If a fraudulent election falls in the woods and no judge is around to hear it, did it fall?)
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To: algore

Please explain the nature and the effect of the mutation.


4 posted on 02/15/2022 12:05:55 PM PST by Arcadian Empire (The Baric-Daszak-Fauci spike protein, by itself, is deadly.)
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To: rightwingcrazy

LOL! My first thought as well. Adam had no comment.


5 posted on 02/15/2022 12:10:38 PM PST by rktman (Destroy America from within? Check! WTH? Enlisted USN 1967 to end up with this? 😕)
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To: Arcadian Empire

Here’s the wiki on it. https://en.wikipedia.org/wiki/CCR5


6 posted on 02/15/2022 12:12:52 PM PST by Valpal1 (Not even the police are safe from the police!!!)
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To: algore

It is. I had an (donor) Allo stem cell transplant. Fortunately my insurance paid for all of it. It also paid for the retrieval of the cells and medical costs for my sister who was my donor.

Recovery is very difficult. The conditioning Chemo they use literally decimated the bone marrow. My blood dna is now exactly my sisters. The process is amazing. They give the cells via a transfusion. The cells make their way to the bone marrow and they then begin the replication process. I grafted in less than a month in which my dna changed to my sisters.

If a female has a male donor. Her blood will show as XY.


7 posted on 02/15/2022 12:14:32 PM PST by HollyB
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To: rightwingcrazy

Wasn’t Eve replaced by Dr. Jill? (well, at least in her own mind)


8 posted on 02/15/2022 12:14:58 PM PST by ProtectOurFreedom (If truckers quit their jobs, society would collapse. If politicians quit their jobs...HALLELUJAH!)
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To: Valpal1

Thank you.


9 posted on 02/15/2022 12:15:31 PM PST by Arcadian Empire (The Baric-Daszak-Fauci spike protein, by itself, is deadly.)
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To: rightwingcrazy
You beat me to the well deserved jibe at the poor English language skills of the author(s) and editors at the Daily Mail, in re: "The World's "First Woman......"
10 posted on 02/15/2022 12:17:29 PM PST by Wuli
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To: HollyB

That sounds too intricate for puny, ignorant men to be attempting. How do you know what the long term side effects are?


11 posted on 02/15/2022 12:20:51 PM PST by BiglyCommentary
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To: fwdude

Yeah like HEP C can be cured.

Both my brothers were “cured” and they both are dead - from HEP C.


12 posted on 02/15/2022 12:23:02 PM PST by 1FreeAmerican
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To: 1FreeAmerican

I had a very good friend also cured of HEP C he is also dead!!


13 posted on 02/15/2022 12:24:38 PM PST by Trump Girl Kit Cat (Yosemite Sam raising hell)
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To: Valpal1

Just as her, I had AML. A stem cell /bone marrow transplant is pretty much the standard treatment for AML, if aggressive mutations are involved. Which I had flt3 and t(4,12). So, it seems that a sct would be her standard treatment without HIV. I’m sure they approached it thru the lense ofva clinical trial to see if the virus would be depleted.

I had to be revaccinated with all childhood vaccines. My immune system memory was deleted thru the conditioning chemo and sct. Basically My immune system was like an infant after the process. I can see how they were curious if it would work the same. The proof will be if any hidden remnant hiv cells survived and begin to multiply.


14 posted on 02/15/2022 12:24:48 PM PST by HollyB
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To: algore

“... but is also so risky that it has been deemed ‘unethical’ to use it on people who do not have a late-stage cancer diagnosis.”

Sound familiar?


15 posted on 02/15/2022 12:27:14 PM PST by SgtHooper (If you remember the 60's, YOU WEREN'T THERE!)
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To: BiglyCommentary

The problems are if the match isn’t good. Development of gvhd - Graft vs host disease can occur. If it’s severe, it can be deadly. The donor cells can attack any organ. I have gvhd in my eyes. My vision sucks. I have some rashes on my legs. This is minor tho. I can never go in the sun as it can flair skin gvhd. My problem is due to the intense chemo snd additional 3 years of daily chemo to keep the aggressive mutation from returning. I have horrendous Neurapathy in both my legs and feet.


16 posted on 02/15/2022 12:29:07 PM PST by HollyB
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To: SgtHooper

She had AML. Sct’s for AML is standard treatment.


17 posted on 02/15/2022 12:29:53 PM PST by HollyB
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To: HollyB

I was referring vaguely to the current medical mentality to forbid IVM or Doxy, and not even because it is too risky, but simply considered unapproved by the prevailing witch doctors.


18 posted on 02/15/2022 12:34:01 PM PST by SgtHooper (If you remember the 60's, YOU WEREN'T THERE!)
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To: SgtHooper

I see. It’s interesting how they pick and chose indeed.


19 posted on 02/15/2022 12:35:01 PM PST by HollyB
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To: fwdude

“They’re “cured,” until they’re not.“

Yeah I’m real wary of the AIDS virus. I think I’d buy that some are immune but cure? I don’t know.


20 posted on 02/15/2022 12:40:57 PM PST by TalBlack (We have a Christian duty and a patriotic duty. God help us.)
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