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Cannabinoids Block Cellular Entry of SARS-CoV-2 and the Emerging Variants
National Library of Medicine - PubMed ^ | January 10th, 2022 | Richard B van Breemen 1 , Ruth N Muchiri 1 , Timothy A Bates 2 , Jules B Weinstein 2 , Hans C L

Posted on 01/13/2022 8:59:08 AM PST by Mariner

Abstract

As a complement to vaccines, small-molecule therapeutic agents are needed to treat or prevent infections by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) and its variants, which cause COVID-19. Affinity selection-mass spectrometry was used for the discovery of botanical ligands to the SARS-CoV-2 spike protein. Cannabinoid acids from hemp (Cannabis sativa) were found to be allosteric as well as orthosteric ligands with micromolar affinity for the spike protein. In follow-up virus neutralization assays, cannabigerolic acid and cannabidiolic acid prevented infection of human epithelial cells by a pseudovirus expressing the SARS-CoV-2 spike protein and prevented entry of live SARS-CoV-2 into cells. Importantly, cannabigerolic acid and cannabidiolic acid were equally effective against the SARS-CoV-2 alpha variant B.1.1.7 and the beta variant B.1.351. Orally bioavailable and with a long history of safe human use, these cannabinoids, isolated or in hemp extracts, have the potential to prevent as well as treat infection by SARS-CoV-2.

(Excerpt) Read more at pubmed.ncbi.nlm.nih.gov ...


TOPICS: News/Current Events
KEYWORDS: vaccines
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huh?
1 posted on 01/13/2022 8:59:08 AM PST by Mariner
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To: Mariner

this is SCIENCE. = systematized knowledge.

it is ILLEGAL at the FDA and CDC,
where the authors are drowned tied to bricks like on Synnax.


2 posted on 01/13/2022 9:02:16 AM PST by Diogenesis (Si vis pacem, para bellum)
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To: Mariner

Smoke’em if you have them, at least take toke on it


3 posted on 01/13/2022 9:02:24 AM PST by srmanuel (`)
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To: Mariner

https://www.dailywire.com/news/cannabis-prevents-covid-infection-in-lab-study


4 posted on 01/13/2022 9:03:04 AM PST by Mariner (War criminal #18)
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To: Mariner

Errrrybody must get stoned ;)


5 posted on 01/13/2022 9:03:06 AM PST by Tx Angel (Insert witty tagline here)
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To: Mariner

Block? By how much? Article doesn’t say. 10%? 50? 75%?


6 posted on 01/13/2022 9:05:21 AM PST by Bob434
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To: Bob434

And what dose and freauency?


7 posted on 01/13/2022 9:05:56 AM PST by Bob434
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To: Bob434

Skip that. Go straight to the Cheetos.


8 posted on 01/13/2022 9:07:43 AM PST by bgill (Which came first, the vax or the virus?)
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To: Tx Angel

I don’t think those compounds are the ones that get you high.


9 posted on 01/13/2022 9:08:21 AM PST by ModelBreaker
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To: Mariner

I would not feel so all alone....

Everybody must get STONED!


10 posted on 01/13/2022 9:08:35 AM PST by Yo-Yo (is the /sarc tag really necessary?)
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To: Bob434

Block? By how much? Article doesn’t say. 10%? 50? 75%?

1%.......i’m in....


11 posted on 01/13/2022 9:08:56 AM PST by heshtesh
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To: Mariner

Just about everything prevents Covid19…. Except the Jab.


12 posted on 01/13/2022 9:09:30 AM PST by P-Marlowe (I got the <ΙΧΘΥΣ>< variant. Catch it. John 3:16)
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To: Mariner

Male pattern baldness, ingrown toenails, ED, cronic vaginitis,
now CV19 theraputic. Is there nothing marijuana won’t cure?
The Miracle Drug./S


13 posted on 01/13/2022 9:12:57 AM PST by Vinnie ( L g Brandon)
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To: Vinnie

It’s a peer reviewed study in a reputable publication.

It’s not some hippie spouting off at a cannabis festival.


14 posted on 01/13/2022 9:16:49 AM PST by Mariner (War criminal #18)
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To: Mariner

Marijuanna has a long proven history of weakening one’s immune system, although those studies have been stopped and hidden away in recent years. Michael Savage used to talk about it all the time on his show.


15 posted on 01/13/2022 9:17:14 AM PST by Golden Eagle (What's in YOUR injection?)
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To: Mariner

This must be why I’ve stayed well for all this time.


16 posted on 01/13/2022 9:22:15 AM PST by SaxxonWoods (If It Aint Woke Don't Fix It.)
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To: Mariner; All
Thank you for referencing that article Mariner. Please note that the following critique is directed at the article and not at you.

We're getting mixed messages on marijuana versus CV19.

Insights welcome.

17 posted on 01/13/2022 9:24:11 AM PST by Amendment10
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To: Mariner
Cannabinoid acids from hemp (Cannabis sativa) were found to be allosteric as well as orthosteric ligands with micromolar affinity for the spike protein.

I could have used these talking points back in the day when my parents found my little stash of seeds and a pipe 😁

18 posted on 01/13/2022 9:24:16 AM PST by capydick (“Within the covers of the Bible are the answers for all the problems men face.)
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To: Golden Eagle

Wife and I have smoked it for 4 decades. Both our doctors recently described our lungs as “perfect”, and our health as unusually good, their descriptions without being asked.


19 posted on 01/13/2022 9:24:45 AM PST by SaxxonWoods (If It Aint Woke Don't Fix It.)
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To: Golden Eagle
Marijuanna has a long proven history of weakening one’s immune system

You don't even know how to spell Marijuana.


20 posted on 01/13/2022 9:26:09 AM PST by dragnet2 (Diversion and evasion are tools of deceit)
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