Yes, but a 44 mag is more common and you can buy ammo everywhere you go.
Speaking of ammo, potent loads with heavy, hard-cast bullets would be helpful in punching through a bear’s skull. Buffalo Bore makes ammo of this sort.
I’ve read that Alaskan guides have been turning to Glock 20s in 10mm for protection. The reasoning is, having more rounds increases the chances of some effective hits.