Wickard is the single case that I hate the most - it allows the Commerce Clause to be used by the Feds to control literally anything that they want to control. I bunch of little girls couldn’t make lemonade in Florida from Florida water, lemons and sugar cane, and sell it only to Florida residents, if the Feds decided to regulate the lemonade market.
The Founders would have started another revolution, just to rid us of Wickard.