The Supreme Court ruled, in Barron v. Baltimore, that the 5th amendment did not apply to state actions. This court case was one of the reasons for the 14th Amendment.
It was in the middle 1830's the slave states stopped considering if slavery was immoral, and considering a way to gradually eliminate it.
The first laws against concealed carry were in the slave states.
“On every question of construction (of the Constitution) let us carry ourselves back to the time when the Constitution was adopted, recollect the spirit of the debates, and instead of trying what meaning may be squeezed out of the text, or invented against it, conform to the probable one in which it was passed.” - Thomas Jefferson
Shall not be infringed is as un-ambigious as you can get.