“Zinc with hydroxychloroquine causes a two-fold hit on the virus. HCQ prevents the virus from entering the cell where it hijacks the reproductive machinery. It also provides pathways into the cell for zinc. At high levels in the cell, zinc destroys the RNA dependent RNA polymeras, which stops the replication process.”
Good summary. Many people who eat well, have enough zinc already but it is likely good practice to administer it anyway with the HCQ. Very cheap insurance, like HCQ itself.
The Zpack should only be given if a definite secondary infection has already set in. The HCQ + Zpack can increase risk of (usually non-lethal) cardiac events. Not so much HCQ byitself, with or without Zinc.
BTW, the Korean study above looks quite good!
The levels of zinc in the cell required to knock out the virus replication process are not high enough, even if you supplement zinc. However, HCQ opens up these pathways so that the zinc given in the treatment go directly into the cells where they raise havoc with the RNA dependent RNA Polyneras (spelling?).