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[So what’s the point of all that? Well, any treatment that is going to be successful HAS to prevent this, what seems to me is probably a pretty characteristic presentation, serious brain injury which is likely already occurring in the seriously ill. It seems to me that no drug is going to get more than a few doses into the patient as all this is occurring. Certainly a drug that is administered IV will get maximal opportunity as it avoids all the pharmacokinetics of absorption, etc. it also has to have a MAJOR impact in those few doses to prevent death or serious disability. (Pretty obviously Remdisivir isn’t it, it has obviously been used in this context and if it was successful we would be hearing “reduces mortality” instead of “shortens hospital stays”)

It is fortunate that the disease progresses to this outcome so rarely.]

You gotta wonder if the differences in symptoms are pure chance, or have to do with differing immune systems, and if so, whether that difference is genetic or related to an individual’s physical conditioning (i.e. weight, exercise routine, etc). As of now, with the exception of China, the Orient appears to been grazed, at most, by this virus. That’s the diametric opposite of what occurred with SARS. And even with China, the stories about crematoria running 24 hours a day seem to have died down. While there are occasional issues with fresh outbreaks, the near-hysteria of the original outbreaks appears to have died down. If there’s a repeat of the original issues, I fully expect Radio Free Asia and Epoch Times to be on top of any breaking news. And yet, in the past month or so, crickets.

Watch the thing about Oxidative Stress again because he points out exactly what the source of risk is for the comorbidities and just how the virus releases those effects to amplify. It really is an excellent presentation of “Oxidative Stress.”

The guy in the vid is an Inf Dis guy from UCSF. I doubt I would agree with his politics but that shouldn’t affect his presentation of the facts. He has another video at 4 PM today that is next and I would bet he explains about the “basement membrane being thrombogenic”.