Posted on 04/28/2020 11:01:22 AM PDT by RushingWater
Didn't mention replication. Whatever. The virus latches to cells rich with ACE receptors. Here is what I have read:
"Your red blood cells carry oxygen from your lungs to all your organs and the rest of your body. Red blood cells can do this thanks to hemoglobin, which is a protein consisting of four “hemes”. Hemes have a special kind of iron ion, which is normally quite toxic in its free form, locked away in its center with a porphyrin acting as it’s ‘container’. In this way, the iron ion can be ‘caged’ and carried around safely by the hemoglobin, but used to bind to oxygen when it gets to your lungs." ...
"Here’s where COVID-19 comes in. Its glycoproteins bond to the heme, and in doing so that special and toxic oxidative iron ion is “disassociated” (released). " ...
"… it’s just too much iron and it begins to overwhelm your lungs’ countermeasures, and thus begins the process of pulmonary oxidative stress. This leads to damage and inflammation, which leads to all that nasty stuff and damage you see in CT scans of COVID-19 patient lungs. "
every critically ill patient follows the same patter. of multi organ failure at end stage. This is NOT new mysterious or unprecedented nor is it sinc deficiency
Sure. But when the black death swept Europe, there was a period when the same thing was true in Europe. There were places that had not yet been touched by it.
Now the question here is, "Are these places having low deaths because the disease has simply not spread through these areas, or are they having low deaths because some other factors are at work stopping the spread or lethality?"
If left to spread without all the precautions we have been taking, will these relatively virus free locations suddenly become overwhelmed with it, or will the virus continue to not be a problem in these areas?
I don't know, and I mistrust anyone who claims to know the answer to that question.
I am hopeful that there are reasons inherent to these locations why the virus has not been so dangerous, and I think with the reopening of businesses, we will soon see the answer to this question.
If it suddenly starts getting worse again, we may have to go through more disease prevention measures again.
If not, great!
Even if a red blood cell can’t replicate a virus, can a virus damage the function of the red blood cell? That’s a theory that has been making the rounds.
I don’t agree. As someone who just went through treatment for cancer (right before all this started), I’m betting the lockdown helped me. Many others in the same boat. The lockdown definitely saved lives.
Yup,I knew when the “flattening” starts,the a-hole left will try to raise it again. I have never hated anyone or anything as much as the left. The only “flattening” the left wants is Trump’s re-election chances as in a true flat line. They are trying to destroy POTUS Trump and MAGA at all costs.
“We Still Don’t Know How the Coronavirus Is Killing Us”
Headline is just to sell “Fear, Uncertainty and Doubt”
We do know how it is killing, who it is killing and who it is not killing.
Isn’t that crazy? I’ve never heard of the thing and to read it was a serious contender before the discovery of Penicillin is outrageous.
I recall wondering if ECMO might be beneficial and was’t surprised to see they are using it. To think they are seriously using that kind of technology now and in a few weeks there may be no patients that ill.
The micro emboli thing is fascinating. Outside of autoimmune vasculitis there isn’t a disease that does this. Look for yourself. ALL the causes of clinical vasculitis are auto immune and hereditary. ALL of them. Not ONE is infectious. Yet here this disease is. But IMHO it isn’t an “inflammatory” vasculitis because it isn’t immune mediated. It’s direct viral attack exposing the basement membrane. I can’t think of a disease that does that.
All of the clinical causes of spontaneous emboli produce large clots. Comparatively. They all produce clots in the mm. range. Here we’re talking clots that are literally microscopic in size. Smaller than a red cell and a red cell is small.
Viral glycoproteins don’t usually get inserted, just the genome. The rest of the virus stays on the outside as a general thing. Now it may “stick” there I would imagine and when the red cell finally gets recycled in weeks or months it gets “processed” by a Macrophage.
I've read that the workers in those plants were in very close proximity to each other.
The deaths in MANY states have held at <10 or <5 per day for about three weeks.
Probably inherent distancing. They aren't so closely packed as they are in New York or China.
I've often said viruses are like fire. You have to have fuel, and it has to be close enough together to catch the fire from other burning fuel. If it's too far away, it won't catch.
People are fuel, and density is a major contributing factor. Less density, less chances of the fire spreading.
At some point when there are 50 virions per red cell maybe. That’s one hell of a viral load.
Those folks may have to start working under conditions like an Operating Room. Which might not have been a bad idea even without the virus. How many millions of pounds of ground meat get thrown out every year?
I just always hated Pathology and trips to the morgue. It’s just awful down there. But when they do posts they take a little standard sample from each organ and drop them in formaldehyde. Then they embed the tissue in paraffin and stain it, usually with just an H&E stain but they can order special stains for special cases. Looking at these slides is where the “pathology” art is really at. Intellectually it is incredible. These will tell the story as the pathologists do what they do. I bet they are already producing some fascinating reading. They will be able to see cerebral microinfarcts that will be correlatable with what is seen on the MRIs.
They’ll see the renal microemboli. They’ll see the denuded vascular endothelial basement membrane where the micro clots form and see it with micro emboli in place. At least that is what I imagine.
Speak for yourself New York magazine. It's allegedly killing plenty of people in New York. It's hardly killed anyone get in South Dakota.
Bingo!
Look at this:
https://www.thelancet.com/pdfs/journals/lancet/PIIS0140-6736(20)30937-5.pdf
Just as I suspected. And notice the monocytes are trying to clean up the mess. Direct viral attack on the vasacular endothelium of every organ.
DUH! Here is probably the answer:
www.webmd.com › Asthma › Guide
Jul 30, 2018 - Without oxygen, your brain, liver, and other organs can be damaged just minutes after symptoms start. Hypoxemia (low oxygen in your blood) ...
It’s obvious to me that Trump is being briefed on all manner of old and new things being proposed and when he mentions them in the briefings the press just does it’s stupid gotcha game instead of honest reporting.
They are engaged in clickbait journalism and too stupid to realize that honest reporting on all these technologies would do as well or better than their petty juvenile gotcha stories. Their heads are so far up their asses, I am amazed every day at the contortions they pull off.
Bless Trump, it’s exhausting dealing with that level of gymnastically gifted stupid.
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