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Will Hydroxychloroquine help fight COVID-19? This Vanderbilt University Medical Center trial is trying to find out
CBS News ^ | 04/18/2020 | By JONATHAN LAPOOK

Posted on 04/18/2020 7:11:12 AM PDT by SeekAndFind

Hydroxychloroquine, which is usually used to treat malaria, has been championed by President Trump for the treatment of COVID-19. But doctors say it's too early to be sure, and small studies have had mixed results.

Dr. Wesley Self at Vanderbilt University Medical Center is leading a clinical trial to see if it really works. "Hydroxychloroquine may help prevent the virus from entering cells in the body and therefore prevent it from replicating more or growing within the body," Self explained.

Tisha Holt, 42, is one of the first people who enrolled. She's been in the Vanderbilt ICU for four days.

She told Self that she feels "weak," and that she has a lot of chest tightness and is "very sick."

"I want it to work," Self said. "I see that it has promise but I also understand most promising drugs that are at this stage of research do not ultimately work."

The drug may raise the risk of an irregular heartbeat, but it has generally been a safe medication. Doctors and patients like Holt don't know who is receiving the drug and who is getting a placebo — the gold standard in research.

"If I can do something to help then I want to do it," Holt said, "and makes me feel better to help someone else."

(Excerpt) Read more at cbsnews.com ...


TOPICS: Culture/Society; News/Current Events
KEYWORDS: coronavirus; covid19; hcqstudy; hcqtrial; hydroxychloroquine; vanderbilt
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To: The Truth Will Make You Free

RE: HCQ + zPack (azithromycin) with no zinc

Well, wasn’t that the successful Dr. Didier Raoult protocol done on over a thousand patients in Marseille, France?


21 posted on 04/18/2020 9:33:21 AM PDT by SeekAndFind (look at Michigan, it will)
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To: catnipman

Have you done a deep dive into that Texas nursing home yet? The doctor, Robin Armstrong, has treated 39 patients at the home and only two were later hospitalized for presumably non-Covid issues (one a fall, and one dehydration). A remaining one is going back and forth but now looks like he’s on the way to recovery (as of 4 or 5 days ago.) I would think those would be spectacular results for a nursing home with a severe outbreak of Covid-19, but the media begs to differ, of course.

The left is feasting on the fact that he’s a staunch Republican and may have treated some dementia patients without talking to the person with the POA first, which they are making out to be the equivalent of the Tuskagee experiment or Nazi experiments, of course.

He used all three, HCQ, azithromycin, and zinc, by the way. News reports have been confusing about the numbers involved. Some say 83 were infected, some 56. None say what happened to the ones that weren’t treated, as far as I can tell.

Just wondering if you have more updated information.


22 posted on 04/18/2020 9:34:11 AM PDT by Norseman (Defund the Left....completely!)
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To: Norseman

“Just wondering if you have more updated information.”

that wasn’t an “official” trial sanctioned by NIH/CDC/FDA/whatever, so there’s nothing to dive into,i.e., no clinical trail webpage with the various trial parameters ...


23 posted on 04/18/2020 9:58:48 AM PDT by catnipman (Cat Nipman: Vote Republican in 2012 and only be called racist one more time!)
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To: catnipman

Yes, I know. Sorry, I didn’t realize you were deep diving into formal trials only. Thanks for the reply.


24 posted on 04/18/2020 10:25:59 AM PDT by Norseman (Defund the Left....completely!)
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To: SeekAndFind
Yes. But it looks like smaller number using it. Tried to find recent articles but all were March, including a 3/18 FR thread.

All this reminds of of an Indian doctor’s recommendation for cancer. If you are on the verge of dying use Western doctors and hospitals. If you have time to get well, make the lifestyle changes Indian doctors prescribe. Our medical system is based on cure, not health.

I’ve also not seen any studies on Vitamin D, although a Freeper commented that no one with a D deficiency became critical. If that’s true, why aren’t we as a nation freely giving D3 across the board? I’d probably be 1/100,000 the cost of an economic shutdown.

Our medical profession needs a serious reformation.

25 posted on 04/18/2020 10:38:53 AM PDT by The Truth Will Make You Free
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To: BushCountry

Sorry, but all wrong. All you are doing is showing your ignorance of proper scientific research. It’s your opinion and you’re entitled to it, but science doesn’t accept opinions.

An appropriate study would have a HCQ only group, an HCQ+Zpak group, a Zpak+Zinc group, a HCQ+Zinc group, and a placebo group at a minimum. That involves a LOT of people and a LOT of time and money.

Note...I think that doctors “should” have the option to prescribe what they feel best, but the needed information for absolute assurance of scientific validity just does not currently exist.


26 posted on 04/18/2020 11:42:00 AM PDT by Wonder Warthog (The Hog of Steel and NRA Life Member)
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To: SeekAndFind

Given that Fauci, Redfield and Birx were willing to report falsified data re: AIDS drugs, I see no reason to expect that they and their Big Pharma-dependent researchers couldn’t also falsify results against HCQ. Already we saw that terrible study from Brazil, clearly meant to discredit the option.


27 posted on 04/18/2020 11:44:26 AM PDT by 9YearLurker
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To: Wonder Warthog

Whatever. They had months for proper science and sat with their thumbs up their butts. The world and the US economy is completely destroyed and a proper study has not been conducted? Trillions of dollars lost. We can afford a billion dollar study.

And lastly, to hell with proper science. With thousands dying daily they should test what seems to be working first. What doctors have reported works. Something that has been used on tens of thousands of patients. Collect all the damn data from every case and review. Perfection is the death of progress, in this case literally.


28 posted on 04/18/2020 7:47:25 PM PDT by BushCountry (thinks he needs a gal whose name doesn't end in ".jpg")
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To: BushCountry

And YOU could have predicted the onset of the virus and which meds needed to be tested before it happened?? If so, you need to be in either Vegas or Monte Carlo and not posting on this forum.

Sorry, but reality doesn’t work that way.


29 posted on 04/19/2020 2:56:04 AM PDT by Wonder Warthog (The Hog of Steel and NRA Life Member)
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To: Wonder Warthog

Sorry again. As of right now, there are active 2,359,332 with 161,950 deaths and 606,675 recovered patients. Scientist have the world’s fastest computers (16 supercomputers to help speed the discovery of vaccines and drugs to combat the novel coronavirus) and Folding@Home’s Cluster computer system available. Yet, they are only now doing a small scale test?

It is mind-boggling how stupid science is.


30 posted on 04/19/2020 7:43:11 AM PDT by BushCountry (thinks he needs a gal whose name doesn't end in ".jpg")
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To: BushCountry
"Scientist have the world’s fastest computers (16 supercomputers to help speed the discovery of vaccines and drugs to combat the novel coronavirus) and Folding@Home’s Cluster computer system available. Yet, they are only now doing a small scale test?"

Models are cheap. Verification experiments are time-consuming and expensive. Models without verification experiments are worthless.

Add to that the fact that there are millions of possible scenarios that "could" happen, and you are asking that which is impossible to do, as, even with just modelling, the number of combinations approaches infinity as a limit.

"It is mind-boggling how stupid science is."

What is really mind-boggling is how uninformed your notions are.

31 posted on 04/19/2020 8:38:11 AM PDT by Wonder Warthog (The Hog of Steel and NRA Life Member)
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To: Wonder Warthog

Ha, ha. What is mind-boggling is how inept science and medical care is. The 4th leading cause of death in the US is medical mistakes. Around 440,000 deaths are attributed to it.

Models without verification are worthless. No, it is the inability to leverage the fastest, smartest, AI machines on the planet to draw an initial conclusion.

We had maybe a million patients treated with Hydroxychloroquine and different combination drugs. We know the results of the treatments (cure and death rate). And we have a million patients that weren’t treated. Out of this, you should be able to determine what has worked or not worked with best with the best analytical machines on the planet.

No I am not saying look up a million possibilities. Just a few. Those treated with Hydroxychloroquine, Hydroxychloroquine and combination drugs, and a similar group not treated (age, health, sex, stage of treatment, etc..). With a million patients to pull from you should be able to narrow down exactly matching cases in the thousands and draw conclusions from the results.

We already have the data on the result. It just needs to be gathered and analyzed.


32 posted on 04/19/2020 9:48:33 AM PDT by BushCountry (thinks he needs a gal whose name doesn't end in ".jpg")
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To: BushCountry

Sorry, but you’re simply clueless and don’t realize it. Further discussion useless. Bye.


33 posted on 04/19/2020 11:36:26 AM PDT by Wonder Warthog (The Hog of Steel and NRA Life Member)
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