Do your patients not have high ferritin levels? If they do, what do you think might be causing it?
I don’t know if this sort of work is worth much but i found it interesting:
https://chemrxiv.org/articles/COVID-19_Disease_ORF8_and_Surface_Glycoprotein_Inhibit_Heme_Metabolism_by_Binding_to_Porphyrin/11938173
Ferritin is also an acute phase reactant as well and can be a no specific indicator of inflammation. I am not seeing a whole lot of elevated ferritin. But even if we were elevated ferritin is the hallmark of hemachromstosis and the solution to that disease is phlebotomy not transfusion.