Posted on 04/06/2020 2:47:01 PM PDT by gasport
This article justifies use of HCQ in mgt of hidradenitis suppurtiva. Pharmacies in NYS can, thus, dispense HCQ to patients with diagnosed HS. HS is a /forme fruste/ of SLE.
HS is aka Undifferentiated Connective Tissue Disease, Latent Lupus, or Incomplete Lupus
Isn’t this common knowledge?
LOL
No
Pretty sure people have been talking about the passengers on the quarantined cruise ships who were on Hydroxychloroquine for that or as an antimalarial not coming down with or becoming carriers of The Wuhan Bioweapon since February.
If it once was not common knowledge it has become common knowledge during the last two months.
HS is not a specified indication allowing dispensation. The article documents a relationship between SLE and HS.
Never heard of HS before today.
My wife has been a Lupus (SLE) patient since 1983. She’s been taking HCQ for 37 years.
Bkmrk.
The description of HS in the article seems different than I’ve understood it; the cysts appear where there are sweat glands AND skin is often in contact with other skin (groin, armpits), not on open/exposed surfaces.
HS is a fairly common, at least to a Dermatologist, unpleasant condition which is difficult to treat. I see more of it than lupus and have never considered them to be related. However one doesn’t prevent the other so they can co-incidentally occur together as this case shows. The anti-inflammatory properties of HCQ help a variety of uncommon skin diseases, not just lupus.
As I put it together, HS is the result of a focal cytokine storm. Haven’t figured out why apocrine glands are targeted. There is probably a unique tissue specific antigen.
My days in histochemistry are long gone.
I have Hidradenitis suppurativa. My treatments have included steroid shots, antibiotics, and incision and drainage. There’s actually no truly effective, long term treatment. I’d never heard of using this drug for it. The link that you posted doesn’t even mention it, as far as I can tell.
The patient in Israel is now on HCQ. The paper doesn’t mention if she was on it prior to onset of HS.
Yep. HS happens where skin rubs against other skin (i.e., groin, armpits, under the breasts in women). But HS is not about cysts (although cysts can be present in patients who have HS, and there is a significant rate of comorbidity with HS and severe cystic acne). HS is about swollen tissue, as well as abscesses filled with fluid. A cyst is something that can be removed as a solid object. But the swollen tissue of HS cannot be removed without also removing healthy tissue (which can permanently affect the patient's ability to move their arms or legs). The abscesses can be drained to some degree, but that can take a very long time, as it's more like squeezing a sponge over and over and over, as opposed to emptying out a balloon. And even then, the abscesses will eventually fill up again, and again, and again.
They say HS is common, but I’d never heard of it until the doctor told me that I had it when I was in my 40s. I’d already been diagnosed with severe cystic acne decades earlier, and had take four courses of Accutane, and had had a huge number of cysts all over my body removed by surgery. One morning I woke up with what I thought was the biggest and most painful cyst that I had ever had. It was all the way from my scrotum to my anus, and I could barely walk. The dermatologist said it was HS, and that was the first time that I’d ever heard of it. They say that between 1 and 4 per cent of the population has it, and I’m skeptical of that claim, because I’d never heard of it until I was diagnosed with it. However, they also say that of those who have it, only 1% of those people actually have stage 3, which is what I had. It’s possible that I’d actually had stage 1 or 2 for decades but I mistakenly thought it was just cysts. Only when it finally swelled up to stage 3 did I get a proper diagnosis. It’s rarely at stage 3 for me. Whenever it gets that big, it always eventually rips open on its own and drains gradually for several days. Stage 3 HS makes even my worst cystic acne seem like a walk in the park. I’ve never had any other illness that hurt so bad that I couldn’t even watch TV when I was lying in bed.
Thanks.
FReepers have gotten to watch medical research realtime.
Disclaimer: Opinions posted on Free Republic are those of the individual posters and do not necessarily represent the opinion of Free Republic or its management. All materials posted herein are protected by copyright law and the exemption for fair use of copyrighted works.