To: muggs
2/25/2020, 5:47:24 PM · 45 of 118 ProtectOurFreedom to saintgermaine I thought you NAC promoters were just selling quackery, so I just Googled "NAC antiviral" and the first hit after the ads was this: N-acetyl-L-cysteine (NAC) inhibits virus replication and expression of pro-inflammatory molecules in A549 cells infected with highly pathogenic H5N1 influenza A virus. All but one of the authors is with the Institute of Medical Virology, Johann Wolfgang Goethe-University Frankfurt, Frankfurt am Main, Germany. Abstract The antioxidant N-acetyl-l-cysteine (NAC) had been shown to inhibit replication of seasonal human influenza A viruses. Here, the effects of NAC on virus replication, virus-induced pro-inflammatory responses and virus-induced apoptosis were investigated in H5N1-infected lung epithelial (A549) cells. NAC at concentrations ranging from 5 to 15 mM reduced H5N1-induced cytopathogenic effects (CPEs), virus-induced apoptosis and infectious viral yields 24 h post-infection. NAC also decreased the production of pro-inflammatory molecules (CXCL8, CXCL10, CCL5 and interleukin-6 (IL-6)) in H5N1-infected A549 cells and reduced monocyte migration towards supernatants of H5N1-infected A549 cells. The antiviral and anti-inflammatory mechanisms of NAC included inhibition of activation of oxidant sensitive pathways including transcription factor NF-κB and mitogen activated protein kinase p38. Pharmacological inhibitors of NF-κB (BAY 11-7085) or p38 (SB203580) exerted similar effects like those determined for NAC in H5N1-infected cells. The combination of BAY 11-7085 and SB203580 resulted in increased inhibitory effects on virus replication and production of pro-inflammatory molecules relative to either single treatment. NAC inhibits H5N1 replication and H5N1-induced production of pro-inflammatory molecules. Therefore, antioxidants like NAC represent a potential additional treatment option that could be considered in the case of an influenza A virus pandemic. NOW you have my attention! What do the microbiologists, virologists, doctors and scientists on FR say?
To: saintgermaine
Thank you. I’ve been taking NAC for years because of COPD. The benifits of it are well known I the COPD community. Could be why I seldom get a cold but if I do it only lasts a day, never more than 2 days.
I ordered more last night. I ordered several supplements. If there is no pandemic. They are all supplements that I use regularly.
If anyone has lots of pain I suggest they stock up on quality kratom if it is legal where they are.
120 posted on
02/28/2020 4:39:19 AM PST by
muggs
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