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To: ifinnegan
Speed is clearly taking precedence over peer review. I'm not a microbiologist, but they did document their methods, logic, reasoning and sources well. They didn't look at "all sorts of organisms" -- they restricted their research to coronaviruses. I don't see any reason to slander this as "ludicrous and non-rigorous." Please elaborate if you have information to discredit this work. Can you explain why should this analysis be expanded beyond coronaviruses to "all sorts of organisms"?
We retrieved all the available coronavirus sequences (n=55) from NCBI viral genome database and we used the GISAID (Elbe & Buckland-Merrett, 2017) to retrieve all available full-length sequences (n=28) of 2019- nCoV as on 27 Jan 2020. Multiple sequence alignment of all coronavirus genomes was performed by using MUSCLE software (Edgar, 2004) based on neighbour joining method. Out of 55 coronavirus genome 32 representative genomes of all category were used for phylogenetic tree development using MEGAX software (Kumar et al., 2018).

On careful examination of the sequence alignment we found that the 2019- nCoV spike glycoprotein contains 4 insertions. We found that these 4 insertions are unique to 2019-nCoV and are not present in other coronaviruses analyzed. Another group from China had documented three insertions comparing fewer spike glycoprotein sequences of coronaviruses . Another group from China had documented three insertions comparing fewer spike glycoprotein sequences of coronaviruses.

So two other research groups in China documented three novel insertions.
32 posted on 01/31/2020 11:42:19 AM PST by ProtectOurFreedom
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To: ProtectOurFreedom

It’s ludicrous and non-rigorous to single out similarity of amino acid sequences of small regions with HIV.

No reason to single out HIV from hundreds of other organisms that also have the same sequence.


53 posted on 01/31/2020 12:53:47 PM PST by ifinnegan (Democrats kill babies and harvest their organs to sell)
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