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To: classyconservative; RummyChick
Here's what I was able to cobble together from available sources as a possible treatment/preventive for a cytokine storm during the SARS scare:

From what I understand, the Spanish Flu (and by extension the new A-H1N1 variant) kills by provoking an immune system hyper-response, sometimes called the “Cytokine Storm” which severely damages the lungs and causes Acute Respiratory Distress (ARD) resulting in oxygen deprivation to the internal organs.

Here is an over the counter (OTC) formula that inhibits some of the major inflammatory mediators, and is now being suggested as a way to stave off ARD. All four factors must be included.

1a) A prescription ACE-2 inhibitor anti-hypertension drug. (Note: Healthy folks w/normal BP would experience a crash in BP, fainting, et al. Those already on other types of BP lowering meds would experience the same.)
-or-
1b) If unavailable, 15,000 IU of Vitamin D* (Note: 15,000 IU is a huge dose of Vitamin D, a fat soluble vitamin. This means excess Vitamin D is stored in the liver, rather being excreted. The half life of Vitamin D is roughly three weeks, and Vitamin D toxicity can cause serious problems)

2) Histamine-1 blocker. Benedryl or the equivalent.

3) Histamine-2 blocker. Tagamet or the equivalent (normally used to block acid reflux.)

4) Ibuprofen. Advil or the equivalent, a prostaglandin blocker.

In addition, it is also recommended to maintain just the MDAR of Vitamin A. Being short of Vitamin A is associated with having an excess of a very powerful inflammatory mediator called TNF-1. But it is easy to take too much Vitamin A, which is toxic. High doses of the provitamin Beta-carotene, which the body converts to Vitamin A, might work as well as straight Vitamin A, and are much less toxic.

Care should be taken to avoid “health foods” that can artificially enhance the immune system, something to be avoided when there is the prospect of ARD.

This was extracted from an earlier thread I've lost track of, with some comments on Vitamin D from NautiNurse, and on ACE-2 inhibitors from reformedliberal added, and a flat out guess on Beta Carotene from me...

I'm not a doctor, and I don't play one on TV, nor did I stay at Holiday Inn last night. Despite that, I bought Benedryl and Tagamet yesterday and will buy Beta-carotene today.

Take that for what it's worth.


155 posted on 01/27/2020 3:11:07 PM PST by null and void (The government wants to disarm us after 243 yrs 'cuz they plan to do things we would shoot them for!)
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To: null and void

N-Acetylcysteine (NAC) is also well documented. I’ll post some of the studies later.


156 posted on 01/27/2020 3:14:42 PM PST by PA Engineer (Liberate America from the Occupation Media.)
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To: null and void

I don’t think you’d have to worry about Vitamin D toxicity if you’re sick, unless you are allergic to it.


161 posted on 01/27/2020 4:49:55 PM PST by goodnesswins (Want to know your family genealogy? Run for political office...")
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To: null and void; GulfMan; RummyChick

Thank you all for your thoughtful replies!


173 posted on 01/27/2020 10:07:05 PM PST by classyconservative
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To: null and void

When the SARS virus was happening I read some information close to this. I was looking for it again, Thanks!

I’ve been taking about 5,000IU of vitamin D a day for two years now and have NOT gotten the annual bronchitis bug that I usually do.


202 posted on 01/28/2020 5:00:51 PM PST by alexandria (Amnesty - Because re-electing democrats is a job Americans just won't do.)
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