Yeah, no place to hide there.
You really don't think that between humint, satellite, radio/cell comm interceptions that the DEA and other agencies don't know where the bosses live? Hell, I could bring up a satellite photo of you house on Google. Either drones or Spec-Op teams could put a major hurt on the heads of the Cartels and their subordinates. It all depends on whether this new Mexican President is willing to take the risk.