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To: wastoute

“the LD 50 THC is probably the safest drug ever discovered”

Far from true.

“the lethal half dose (LD50) for THC in humans is estimated to be around 30 mg/kg. This means that approximately 2 grams (.07 ounces) of pure THC has a 50% chance of killing a 150 pound man.” (https://www.ncbi.nlm.nih.gov/pubmed/24598271)

The mechanisms of death are “marked increase in heart rate or supine blood pressure”.

Concentrated THC derivatives consisting of up to 80% THC are now available - one tenth of an ounce of these would contain a LD50 dose of 2 grams of THC.


30 posted on 09/07/2019 5:38:11 AM PDT by BeauBo
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To: BeauBo

Just stop, your ignorance is extreme and everyone who has any familiar with the subject is going to spot that right away. You sound like AOC talking about guns.


36 posted on 09/07/2019 5:43:35 AM PDT by thoughtomator (... this has made a lot of people very angry and been widely regarded as a bad move.)
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To: BeauBo

If you want to really talk about drug safety you have to talk about Therapeutic Index or “How many multiples of the Effective Dose 50 does it take to reach the LD 50?” Again, THC is about the safest drug ever discovered. Or look at the MOE, Margin of Exposure. In purely objective terms THC is MUCH safer than alcohol, aspirin, or Tylenol.


41 posted on 09/07/2019 5:52:13 AM PDT by wastoute (Government cannot redistribute wealth. Government can only redistribute poverty.)
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To: BeauBo

That would account for all the huge amount of dead people killed by pot...

Seems legit as f***.


43 posted on 09/07/2019 5:52:59 AM PDT by chris37 (Monday, March 25 2019 is Maga Day!)
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To: BeauBo
“the lethal half dose (LD50) for THC in humans is estimated to be around 30 mg/kg.

That estimate is an extrapolation from IV administration to lab rats. They've been unable to kill larger lab mammals with any dose of THC.

91 posted on 09/07/2019 7:15:28 AM PDT by NobleFree ("law is often but the tyrant's will, and always so when it violates the right of an individual")
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