Yep, but even a 5” Vaquero with hot, heavy hard cast .45s would do ya good and is a little lighter for hiking than my 6” Redhawk.
I have 2, 5.5” ‘old style’ vaqueros in .45 Colt. One bisley one regular. I used to use them to shoot cowboy action matches. I have loaded them for hunting with 250 and 300 grain jacketed soft points from 1100 to 1400 FPS. This should stop most critters. I like hard cast and have loaded them too.